CAncer, NUtrition and Taste - Validation of the CANUT-QVA Questionnaire on Eating Habits in Cancer Patients

CAncer, NUtrition and Taste - Validation of the CANUT-QVA Questionnaire on Eating Habits in Cancer Patients

Sponsors

Lead Sponsor: Hospices Civils de Lyon

Source Hospices Civils de Lyon
Brief Summary

Cancer patients are at high risk of undernutrition, which is generally more pronounced for solid tumours (upper digestive tract, Ear Nose and Throat (ENT), bronchial tubes). This undernutrition leads to major weight loss and cachexia, and may represent the first sign of a call for a diagnosis of cancer. Cancer-related undernutrition is multi-factorial origins and has multiple consequences.

Chemotherapy treatments can induce various adverse effects in patients, including sensory disturbances at the beginning of treatment in addition to disturbances that may already be present before any treatment. The alteration of taste and odour, observed in 86% of patients, can induce a change in food preferences, promote the development of aversions, and therefore, lead to a significant reduction in the pleasure of eating. Loss of appetite, decreased food intake and the development of aversions to certain foods are situations experienced by a large proportion of patients treated with chemotherapy.

The assessment of taste disorders in patients treated with chemotherapy is established through the use of questionnaires, interviews and taste tests.

Changes in the perception and identification of salty, sweet, bitter and sour flavours are common in patients treated with chemotherapy.

As regards food products, patients report developing olfactory hypersensitivity mainly for food of animal origin, in particular for odours of fish, frying, cheese and eggs.

The CANUT project aims to study the effect of pathology and chemotherapy on gustatory and olfactory mechanisms, and in particular on interindividual differences in the perception and appreciation of food.

In order to monitor the evolution of patients' eating habits over time, the diet-related quality of life questionnaire (CANUT-QVA) was constructed from items selected from the Well-being related to Food questionnaire (WELLBFQ) after eliminating questions that were too general or expressed in terms of importance to use perception-related responses as a priority.

After this part, an evaluation of the 9 dimensions of the CANUT-QVA questionnaire will be performed.

Overall Status Recruiting
Start Date December 24, 2019
Completion Date March 2020
Primary Completion Date March 2020
Study Type Observational
Primary Outcome
Measure Time Frame
Validate the 9 dimensions of the CANUT-QVA questionnaire identified during the general population analysis. Day 0 (at patient inclusion)
Enrollment 200
Condition
Intervention

Intervention Type: Other

Intervention Name: Evaluation of the 9 dimensions of the CANUT-QVA questionnaire

Description: Evaluation of the contribution of a new questionnaire by patients with solid or hematological cancer according to 9 dimensions: Making food Place where the meals are eaten Eating and drinking: Nutrition Eating and drinking: The pleasure of tasting, chewing Eating and drinking: Satiated, well being Food preparation: Supply, choice, presentation Eating and drinking: Feelings After eating: heaviness, discomfort, hunger Taste/Odour Problems to confirm the number and structure of factors obtained at the end of the pre-study and to remove redundant questions.

Arm Group Label: Patients with solid or hematological cancer

Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- Patient with solid or hematological cancer (any stage of disease and any treatment) diagnosed within 12 months of inclusion.

- Patient who does not object to participate in the trial

- Patient affiliated to a social security system

Exclusion Criteria:

- Minor patient (age <18 years).

- Patient under trusteeship, curatorship or protective measures.

- Patient who has already completed the questionnaire.

- Patient not sufficiently able to speak French to answer the questionnaire

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

Overall Contact

Last Name: Pierre Jean SOUQUET, PR

Phone: 4 78 86 37 74

Phone Ext.: +33

Email: [email protected]

Location
Facility: Status: Contact: Contact Backup: Investigator: Hospices Civils de Lyon, Groupement Hospitalier Lyon Sud, Service pneumologie Pierre Jean SOUQUET, PR 4 78 86 37 74 +33 [email protected] Pierre Jean SOUQUET, PR Principal Investigator
Location Countries

France

Verification Date

January 2020

Responsible Party

Type: Sponsor

Has Expanded Access No
Condition Browse
Arm Group

Label: Patients with solid or hematological cancer

Description: All the patients complete the CANUT-QVA questionnaire

Acronym CANUT-QVA
Study Design Info

Observational Model: Cohort

Time Perspective: Prospective

Source: ClinicalTrials.gov