Impact of OCT Imaging on Decision Making During PCI in ACS Patients

Impact of Optical Coherence Tomography Imaging on Decision-making During Percutaneous Coronary Intervention in Patients Presented With Acute Coronary Syndromes

Sponsors

Lead Sponsor: Assiut University

Collaborator: Wakayama Medical University

Source Assiut University
Brief Summary

Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and stent optimization.

Detailed Description

OCT can be used in acute coronary syndrome (ACS). ACS has more complex culprit lesion morphologies and larger extent of coronary atherosclerosis compared with stable coronary artery disease. The detailed vascular information obtained by OCT may impact PCI in ACS, and which may improve acute results and late outcomes of PCI. Stent expansion immediately after PCI is a strong predictor of late outcomes of PCI, and it is associated with late clinical outcomes in many previous trials.

Overall Status Completed
Start Date 2019-01-01
Completion Date 2020-04-30
Primary Completion Date 2020-03-31
Study Type Observational
Primary Outcome
Measure Time Frame
Percent difference in lumen expansion in stent treated lesion Immediately after the procedure
Secondary Outcome
Measure Time Frame
Clinical outcomes at 1 year follow up During 1 year following the index procedure
Enrollment 390
Condition
Intervention

Intervention Type: Device

Intervention Name: OCT-guided PCI

Description: using optical coherence tomography imaging to help PCI procedure

Arm Group Label: OCT-guided PCI

Eligibility

Sampling Method:

Non-Probability Sample

Criteria:

Inclusion Criteria: - Patients presented with acute coronary syndrome. - PCI was done to them with stent implantation. Exclusion Criteria: - Multivessel PCI at the index procedure. - Patients with ACS due to graft failure post CABG. - Patients treated with no stent implantation.

Gender:

All

Minimum Age:

16 Years

Maximum Age:

N/A

Healthy Volunteers:

No

Overall Official
Location
Facility: Wakayama Medical University
Location Countries

Japan

Verification Date

2020-06-01

Responsible Party

Type: Principal Investigator

Investigator Affiliation: Assiut University

Investigator Full Name: Amir Khalifa Mahfouz Khalifa

Investigator Title: Principle investigator, Cardiology department

Keywords
Has Expanded Access No
Condition Browse
Arm Group

Label: OCT-guided PCI

Description: PCI procedure was done with intra-coronary imaging OCT.

Label: Angiography-guided PCI

Description: PCI procedure was done without any intra-coronary imaging assistance, guided by angiography alone

Patient Data No
Study Design Info

Observational Model: Case-Control

Time Perspective: Retrospective

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