Effects of tDCS on Anaerobic Power of Lower Limb Muscles

Effects of tDCS on Mechanical Power of the Leg Extensor Muscles of Healthy Subjects

Anaerobic power and capacity are essential in many human activities, especially during sports practice that demand a high strength and power of the limbs. Transcranial direct current stimulation is a noninvasive technique that can modulate motor brain areas involved in motor functions and has the potential to optimize muscle capacity. However, their effects on mechanical power are lacking.

This study aims to investigate the effects of transcranial direct current stimulation (tDCS) on mechanical power in healthy subjects.

Study Overview

• Status: Completed
• Conditions: Healthy Volunteers
• Intervention / Treatment: Device: Transcranial direct current stimulation

Detailed Description

In this study, a randomized, crossover, double-blind, placebo-controlled experimental design will be used. The 50 participants will be randomized into two groups: (1) Anodal tDCS(real) and (2) Sham tDCS. A single session of anodal and sham tDCS will be performed on each task (pre and post-jump test).

All evaluations will be performed by a single researcher who, like the participants, will not know which stimulation group will be participating. Subjects who agree to the conditions and sign the consent form may participate in the study. Participants who meet the eligibility criteria will be included in the study.

• Study Type: Interventional
• Enrollment (Actual): 50
• Phase: Phase 2; Phase 3

Contacts and Locations

Study Locations

• Brazil
  • Piauí
    • Parnaíba, Piauí, Brazil, 64202020
      • Department of Physical Therapy. Federal University of Piaui

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 35 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Healthy subjects with no complaints of pain or any kind of discomfort in the musculoskeletal system

Exclusion Criteria:

• Musculoskeletal or neurological disorder
• Under medication
• Previous treatment with tDCS

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: tDCS (anodal); tDCS: 20 minutes, 2mA, over the motor cortex representation of lower limbs.	Device: Transcranial direct current stimulation; Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation (NIBS) technique that has been investigated for the management of various health conditions. However, its ergogenic effect still has controversial results.
Sham Comparator: tDCS (sham); tDCS: 20 minutes (but 30s ON), 2mA, over the motor cortex representation of lower limbs.	Device: Transcranial direct current stimulation; Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation (NIBS) technique that has been investigated for the management of various health conditions. However, its ergogenic effect still has controversial results.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean anaerobic power	Mean anaerobic power will be evaluated by assessing the ground reaction forces (GRF) and the number of jumps in each test by means of the kinetic analysis of the 60-second vertical jump test (Bosco's Test).	Pre and Post-test (immediately after tDCS)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Peak anaerobic power	Peak anaerobic power will be evaluated by assessing the ground reaction forces (GRF) and the number of jumps in each test by means of the kinetic analysis of the 60-second vertical jump test (Bosco's Test).	Pre and Post-test (immediately after tDCS)
Fatigue index	Fatigue index will be evaluated by assessing the ground reaction forces (GRF) and the number of jumps in each test by means of the kinetic analysis of the 60-second vertical jump test (Bosco's Test). The fatigue index corresponds to the power reduction rate expressed as a percentage and reveals the degree of reduction in the ability to produce strength and maintain exercise.	Pre and Post-test (immediately after tDCS)
Rating of perceived exertion	The subjective feeling of effort will be assessed by the Borg scale for perceived effort. This is a 15-point numerical scale that ranges from 6 to 20, where 6 means "no exertion at all" and 20 means "maximal exertion."	Post-test (immediately after tDCS)

Collaborators and Investigators

• Sponsor: Universidade Federal do Piauí
• Investigators: Principal Investigator: Fuas A Hazime, PhD, Department of Physical Therapy. Federal University of Piaui

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2021
• Primary Completion (Actual): February 28, 2021
• Study Completion (Actual): April 29, 2021

Study Registration Dates

• First Submitted: July 7, 2020
• First Submitted That Met QC Criteria: July 9, 2020
• First Posted (Actual): July 13, 2020

Study Record Updates

• Last Update Posted (Actual): May 3, 2021
• Last Update Submitted That Met QC Criteria: April 29, 2021
• Last Verified: April 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: tDCS and anaerobic power

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No