Ultrasonographic Evaluation of Abdominal Muscle Thickness Symmetry and Correlation With Pulmonary Function

Ultrasonographic Evaluation of Abdominal Muscle Thickness Symmetry and Correlation With Pulmonary Function Test in Adolescent Idiopathic Scoliosis

We aimed in this study:

1. To compare the ultrasonographic measurements of the abdominal muscles thickness symmetry in patients with adolescent idiopathic scoliosis (AIS) and adolescent healthy individuals
2. To investigate the effect of measured thickness and symmetry on pulmonary function test.

Study Overview

• Status: Completed
• Conditions: Adolescent Idiopathic Scoliosis; Muscle Physiology
• Intervention / Treatment: Diagnostic test: Bilaterally abdominal muscle thickness with ultrasonography

Detailed Description

This cross-sectional,case-control clinical study included 40 patients diagnosed with AIS and 40 age and gender -matched healthy individuals. AIS group was evaluated for localization of curvature and degree of curvature. Ultrasonographic measurements and were performed of bilaterally abdominal muscle thickness in both groups. Spirometry evaluation was performed in both groups. Intragroup and intergroup data were compared.

• Study Type: Observational
• Enrollment (Actual): 80

Contacts and Locations

Study Locations

• Turkey
  • Istanbul, Turkey, 34192
    • Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 10 years to 18 years (Child, Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

10-18 years old patient with AIS diagnosis 10-18 years old healthy adolescent volunteer

Description

Inclusion Criteria:

• Cobb angle over 10 degrees in radiological evaluation
• Between the ages of 10-18 and diagnosed with AIS by a specialist physiatrist

Exclusion Criteria:

• History of previous spinal surgery
• Patients using brace
• Those with any diagnosis of scoliosis other than AIS
• Those with a history of neuromuscular disease
• Previous spinal surgery
• Patients with neurological deficits on examination
• Patients with acute or chronic lung pathology
• Patients with abdominal surgery or injury
• Double curve or multiple curve
• Patients with concomitant chronic diseases
• The child's legal guardian does not allow it to take the tests

The control group:

• 10-18 volunteer adolescents without any health problems,
• In clinical evaluation: Healthy adolescents (without any asymmetric findings on three-way inspection, Adam's forward bend test and scoliometer) were included.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Adolescent idiopathic scoliosis; Ultrasonographic measurements were performed of bilaterally abdominal muscle thickness of AIS patients diagnosed by a specialist. Spirometry evaluation was performed by the investigator	Diagnostic test: Bilaterally abdominal muscle thickness with ultrasonography; AIS group was evaluated for localization of curvature and degree of curvature. Ultrasonographic measurements were performed of bilaterally abdominal muscle thickness in the supine and standing positions in both groups. Spirometry evaluation was performed in both groups; Other Names: Spirometry
Adolescent healthy individuals; Healthy adolescents aged 10-18 were selected. Ultrasonographic measurements were performed of bilaterally abdominal muscle thickness. Spirometry evaluation was performed by the investigator.	Diagnostic test: Bilaterally abdominal muscle thickness with ultrasonography; AIS group was evaluated for localization of curvature and degree of curvature. Ultrasonographic measurements were performed of bilaterally abdominal muscle thickness in the supine and standing positions in both groups. Spirometry evaluation was performed in both groups; Other Names: Spirometry

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Abdominal Muscle Thickness Symmetry	bilateral ultrasonographic millimetric measurement	during evaluation, an average of 45 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Spirometry	Forced expiratory volume 1 (FEV1), Forced vital capacity (FVC), FEV1/FVC, Peak expiratory flow (PEF)	during evaluation, an average of 30 minutes
Cobb angle	Measurements were made on orthoroentgenogram, Grouped as Cobb angle <20 and Cobb angle ≥20	during evaluation, an average of 30 minutes

Collaborators and Investigators

• Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
• Investigators: Principal Investigator: Muhsin DORAN, MD, Istanbul Physical Medicine Rehabilitation Training and Research Hospital; Study Chair: Kadriye Öneş, Assoc Prof, Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Publications and helpful links

General Publications

• Teyhen DS, Gill NW, Whittaker JL, Henry SM, Hides JA, Hodges P. Rehabilitative ultrasound imaging of the abdominal muscles. J Orthop Sports Phys Ther. 2007 Aug;37(8):450-66. doi: 10.2519/jospt.2007.2558.
• Newton PO, Faro FD, Gollogly S, Betz RR, Lenke LG, Lowe TG. Results of preoperative pulmonary function testing of adolescents with idiopathic scoliosis. A study of six hundred and thirty-one patients. J Bone Joint Surg Am. 2005 Sep;87(9):1937-46. doi: 10.2106/JBJS.D.02209.
• Linek P. Body Mass Normalization for Lateral Abdominal Muscle Thickness Measurements in Adolescent Athletes. J Ultrasound Med. 2017 Sep;36(9):1851-1857. doi: 10.1002/jum.14218. Epub 2017 May 15.
• Yang HS, Yoo JW, Lee BA, Choi CK, You JH. Inter-tester and intra-tester reliability of ultrasound imaging measurements of abdominal muscles in adolescents with and without idiopathic scoliosis: a case-controlled study. Biomed Mater Eng. 2014;24(1):453-8. doi: 10.3233/BME-130830.
• Dreimann M, Hoffmann M, Kossow K, Hitzl W, Meier O, Koller H. Scoliosis and chest cage deformity measures predicting impairments in pulmonary function: a cross-sectional study of 492 patients with scoliosis to improve the early identification of patients at risk. Spine (Phila Pa 1976). 2014 Nov 15;39(24):2024-33. doi: 10.1097/BRS.0000000000000601.

Study record dates

Study Major Dates

• Study Start (Actual): April 15, 2019
• Primary Completion (Actual): December 16, 2019
• Study Completion (Actual): April 1, 2021

Study Registration Dates

• First Submitted: September 24, 2020
• First Submitted That Met QC Criteria: September 26, 2020
• First Posted (Actual): September 29, 2020

Study Record Updates

• Last Update Posted (Estimated): January 23, 2024
• Last Update Submitted That Met QC Criteria: January 20, 2024
• Last Verified: January 1, 2024

More Information

Terms related to this study

• Keywords: Ultrasonography; Spirometry; Cobb angle; Imbalance; Abdominal muscle
• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Spinal Diseases; Bone Diseases; Spinal Curvatures; Scoliosis
• Other Study ID Numbers: IstPMRTRH-SCO1

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No