The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis

June 14, 2021 updated by: Uğur OVACIK, Istanbul Aydın University

Upper Limb Assessment in Multiple Sclerosis: The Minnesota Manual Dexterity Test As A Measure Of Hand Function

The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Upper limb can be affected even in early stage in people with Multiple Sclerosis (pwMS). Manual dexterity is important to maintain upper limb function and 9-Hole Peg Test (9HPT) is used as gold standard to assess dexterity in pwMS. There are no studies evaluating manual dexterity with the Minnesota Manual Dexterity Test (MMDT) in pwMS. This study aims to:

  1. reporting the results of manual dexterity using the Minnesota Manual Dexterity Test and comparing the test results with healthy volunteers,
  2. examining the relationship between MMDT and 9HPT, ABILHAND, grip strength, pinch strength, fatigue.

Study Type

Observational

Enrollment (Actual)

80

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
    • Küçükçekmece
      • Istanbul, Küçükçekmece, Turkey
        • Istanbul Aydin University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

16 years to 63 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Test group: 80 people with multiple sclerosis will be evaluated. Inclusion and exlusion criteria listed above. Control group: 40 healthy volunteers with demographic characteristics similar to people with multiple sclerosis will be evaluated to compare people with multiple sclerosis.

Description

Inclusion Criteria:

  • (1) age 18-65;
  • (2) definitive diagnosis of MS according to McDonald criteria;
  • (3) ability to read and write in Turkish.

Exclusion Criteria:

  • (1) acute attacks of MS (within 3 months);
  • (2) cognitive impairment (Mini Mental test result 24 points and below);
  • (3) having spasticity (3 and above according to Modified Ashworth Scale)
  • (4) any chronic disease other than MS;
  • (5) being addicted to alcohol or drugs,

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Only
  • Time Perspectives: Cross-Sectional

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Test Group
people with multiple sclerosis
Other: Test Group
Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.
Control Group
healthy volunteers
Other: Control Grup
Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Minnesota Manual Dexterity Test
Time Frame: baseline (on the predetermined assessment day)
to assess manual dexterity, higher scores mean a worse outcome.
baseline (on the predetermined assessment day)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
9-Hole Peg Test
Time Frame: baseline (on the predetermined assessment day)
to assess manual dexterity. higher scores mean a worse outcome.
baseline (on the predetermined assessment day)
ABILHAND
Time Frame: baseline (on the predetermined assessment day)
to assess for performance of activity. score range 0-46 point, higher scores mean a better outcome.
baseline (on the predetermined assessment day)
grip strength
Time Frame: baseline (on the predetermined assessment day)
using hand dynamometer. higher scores mean a better outcome.
baseline (on the predetermined assessment day)
pinch strength
Time Frame: baseline (on the predetermined assessment day)
using pinchmeter. higher scores mean a better outcome.
baseline (on the predetermined assessment day)
Fatigue Severity Scale
Time Frame: baseline (on the predetermined assessment day)
to assess fatigue. score range 0-7 point, higher scores mean a worse outcome.
baseline (on the predetermined assessment day)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istanbul Aydın University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 2, 2021

Primary Completion (Actual)

May 2, 2021

Study Completion (Actual)

May 16, 2021

Study Registration Dates

First Submitted

January 19, 2021

First Submitted That Met QC Criteria

January 21, 2021

First Posted (Actual)

January 22, 2021

Study Record Updates

Last Update Posted (Actual)

June 15, 2021

Last Update Submitted That Met QC Criteria

June 14, 2021

Last Verified

June 1, 2021

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2020/03

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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