Comparing EVCO and EVOO

February 3, 2021 updated by: Ziyaerokaymetin, Ankara City Hospital Bilkent

Comparing Acute Effects of Extra Virgin Coconut Oil and Extra Virgin Olive Oil Consumption on Appetite and Food Intake in Normal Weight and Obese Male Subjects

The aim of this study is to compare acute effects of consuming extra virgin coconut oil (EVCO) as a source of medium chain fatty acids and extra virgin olive oil (EVOO) as a source of long chain fatty acids in normal weight and obese subjects.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Twenty male subjects (10 normal weight; 10 obese) consumed breakfast meals containing skimmed milk, fat-free white cheese, bread and EVCO (25 g) or EVOO (25 g). Visual analog scale evaluations, resting metabolic rate measurements and selected blood parameters analysis (glucose, triglyceride, insulin and plasma peptide YY) were performed before and after the test breakfast meals. In addition, energy intakes were evaluated by ad libitum lunch meal at 180 min.

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Ankara, Turkey
        • Presidency of Republic of Turkey Health Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 40 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • Metabolically healthy
  • Aged 19-40 years
  • Normal weight (BMI=18.5-24.9 kg/m²) and obese men (BMI=30-34.99 kg/m²)

Exclusion Criteria:

  • smoking,
  • alcohol consumption,
  • weight gain/loss recently (> %5, in three months),
  • any genetic and metabolic diseases,
  • any food allergy/intolerance,
  • any medication,
  • restrained eating habits.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Normal weight
Normal weight subjects (BMI=18.5-25)
Other: Extra virgin coconut oil or extra virgin olive oil
Subjects consumed standard breakfast meals containing "extra virgin coconut oil" or "extra virgin olive oil"
Experimental: Obese
Obese subjects (BMI=30-34.99)
Other: Extra virgin coconut oil or extra virgin olive oil
Subjects consumed standard breakfast meals containing "extra virgin coconut oil" or "extra virgin olive oil"

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Energy expenditure change
Time Frame: 0, 60, 120, 180 minutes
kcal
0, 60, 120, 180 minutes
Subjective appetite feelings change
Time Frame: 0, 30, 60, 120, 180 minutes
visual analogue scales rating (0-10 cm)
0, 30, 60, 120, 180 minutes
glucose change
Time Frame: 0, 30, 60, 120, 180 minutes
mg/dl
0, 30, 60, 120, 180 minutes
insulin change
Time Frame: 0, 30, 60, 120, 180 minutes
mU/L
0, 30, 60, 120, 180 minutes
peptide YY change
Time Frame: 0, 30, 60, 120, 180 minutes
pg/dl
0, 30, 60, 120, 180 minutes
triglycerides change
Time Frame: 0, 30, 60, 120, 180 minutes
mg/dl
0, 30, 60, 120, 180 minutes
Ad libitum energy intake
Time Frame: 180 minute
kcal
180 minute

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara City Hospital Bilkent

Collaborators

Hacettepe University

Investigators

  • Principal Investigator: Ziya Erokay Metin, Dr., Ankara City Hospital Bilkent
  • Study Chair: Pelin Bilgiç, Assoc. Prof., Hacettepe University
  • Study Chair: Mercan Merve Tengilimoğlu Metin, Assis. Prof., Hacettepe University
  • Study Chair: Muzaffer Akkoca, Assoc. Prof., Saglik Bilimleri Universitesi

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 3, 2019

Primary Completion (Actual)

June 3, 2019

Study Completion (Actual)

June 3, 2019

Study Registration Dates

First Submitted

January 20, 2021

First Submitted That Met QC Criteria

February 3, 2021

First Posted (Actual)

February 4, 2021

Study Record Updates

Last Update Posted (Actual)

February 4, 2021

Last Update Submitted That Met QC Criteria

February 3, 2021

Last Verified

February 1, 2021

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • EVCO

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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