- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05076487
Effects of Episodic Food Insecurity in African American Women With Obesity (RESPONSES)
December 12, 2023 updated by: Candice A. Myers, Ph.D., Pennington Biomedical Research Center
Effects of Episodic Food Insecurity on Psychological and Physiological Responses in African American Women With Obesity
The objective of this exploratory/developmental study is to investigate the episodic nature of food insecurity as a stressor via responses in body weight and psychological and physiological parameters longitudinally.
Sixty African American women with obesity will be enrolled.
Pennington Biomedical Research Center will coordinate this longitudinal study and measure 1) daily body weight remotely over 22 weeks and 2) psychological and physiological parameters via clinic assessments at the beginning and end of 22 weeks as well as assess episodes of food insecurity and stress on a weekly basis.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment (Actual)
60
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Louisiana
-
Baton Rouge, Louisiana, United States, 70808
- Pennington Biomedical Research
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 65 years (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Sampling Method
Non-Probability Sample
Study Population
African American women aged 18-65 with obesity
Description
Inclusion Criteria:
- willing to provide written informed consent
- female
- self-reported race of African American or more than one race in which African American is identified
- 18 to 65 years of age
- BMI 30 to 50 kg/m2
- reported income ≤ 250% of the federal poverty level
- ability to complete questionnaires in English
- willing to archive blood and urine samples
- willing to fast for a minimum of 8-10 hours prior to clinic visits
Exclusion Criteria:
- male
- self-reported race other than African American or more than one race in which African America is not identified
- reported income > 250% of the federal poverty level
- given birth within the past 6 months, currently pregnant, or plans to become pregnant within 6 months
- currently breastfeeding
- currently participating in a weight loss program
- current use of prescription or OTC medication specifically for weight loss
- recent weight loss (+/-5% weight change in last 6 months by self-report). If ppt is on a prescription medication that impacts weight but meets weight stability criteria (+/-5% weight change in last 6 months by self-report), ppt will be deemed eligible
- past bariatric surgery within the past 5 years or plans for bariatric surgery within 3 months
- active cancer or cancer treatment
- serious digestive disorders that significantly alter metabolism and weight (like uncontrolled inflammatory bowel disease)
- other conditions that affect metabolism or body weight
- current diagnosis and active treatment for alcoholism or other illicit drugs of abuse
- uncontrolled significant thyroid disorder (controlled = 6 months of medication)
- uncontrolled significant diabetes (FBS >250) or hypertension (BP >180/100)
- current diagnosis or treatment for heart failure
- serious psychiatric illness, including bipolar disorder and schizophrenia
- current or recent diagnosis (within last 5 years) of an eating disorder
- persons who weigh more than 380 pounds (due to scale)
- not willing to be able to re-contacted
- are unable to utilize devices and/or applications as required for study participation
- have another member of the household (same address) that is a participant in RESPONSES
- other conditions that affect metabolism or body weight as determined by the PIs and MI
- presence of any cognitive, psychiatric, behavioral, or medical disorder that, in the opinion of the PIs or MI may interfere with study participation
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
African American Women with Food Security
30 African American women with obesity who are food secure
|
African American Women with Food Insecurity
30 African American women with obesity who are food insecure
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Body weight
Time Frame: 22 weeks
|
Change in body weight
|
22 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Candice A Myers, PhD, Pennington Biomedical Research
- Principal Investigator: John W Apolzan, PhD, Pennington Biomedical Research
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
November 1, 2021
Primary Completion (Actual)
November 29, 2023
Study Completion (Actual)
November 29, 2023
Study Registration Dates
First Submitted
September 30, 2021
First Submitted That Met QC Criteria
September 30, 2021
First Posted (Actual)
October 13, 2021
Study Record Updates
Last Update Posted (Estimated)
December 13, 2023
Last Update Submitted That Met QC Criteria
December 12, 2023
Last Verified
December 1, 2023
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- PBRC 2021-022
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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