Effects of Proprioceptive Training With Routine PT on Gross Motor Function in Spastic Quadriplegic CP

Effects of Proprioceptive Training in Addition to Routine Physical Therapy on Gross Motor Function in Children With Spastic Quadriplegic Cerebral Palsy: A Randomized Control Trial

The proprioceptive training with a therapy regime enhances the body's somatosensory input that in result changes the body to be more functional in different types of interactions. This study is dedicated to finding out how much proprioception training is helpful in gross motor function level improvement and enhances functional activities of CP children

Study Overview

• Status: Completed
• Conditions: Cerebral Palsy
• Intervention / Treatment: Other: Proprioceptive Training; Other: Routine Physical Therapy

Detailed Description

Proprioception plays an important role in the correct execution of efferent motor performance as 70% of cerebral palsy population have deficit in receiving somatosensory signals3. Tradition physical therapy exercises including strengthening followed by stretching etc. should be reviewed and the therapy must be more oriented to overall individual growth and development31. There is a need to push the cerebral palsy population to be exercised with proprioceptive stimulation for their maximum participation in the activities of daily life including both personal and social aspects. The proprioceptive training with a therapy regime enhances the body's somatosensory input that in result changes the body to be more functional in different types of interactions. This study is dedicated to finding out how much proprioception training is helpful in gross motor function level improvement and enhances functional activities of CP children.

• Study Type: Interventional
• Enrollment (Actual): 52
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Lahore, Punjab, Pakistan, 54000
      • The University of Lahore Teaching Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 1 year to 5 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Children with the diagnosis of Cerebral Palsy (Spastic quadriplegia)
• Ages of 1 to 5 years
• Both males and females
• Alert and responsive to verbal and non-verbal commands
• Modified Ashworth Sale grade 1 to 2
• Gross Motor Function Classification System level 1V and V

Exclusion Criteria:

• Children under the botox treatment for tone management (botulinum injections)
• Diagnosed with any disease other than spastic quadriplegic cerebral palsy i.e. congenital heart defects, epilepsy, recurrent pneumonia, skin infections etc.
• Children underwent any surgery i.e. tenotomy (tendon release), recent heart surgery,
• Recent fracture and subluxation/dislocation due to fall or poor handling
• Any contracture or deformity on upper extremities, lower extremities and spine i.e. flexion contractures, club foot, scoliosis

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Group A; NDT- age appropriate Transitions (age appropriate) Milestones training (age appropriate) Proprioceptive Input- age appropriate (Pushups Static quadruped, squat sitting, trampoline, hopping etc. With weights and splints for joint to joint approximation)	Other: Proprioceptive Training; Proprioceptive Training using increased joint to joint approximation through ankle weights and joint splints.
Active Comparator: Group B; NDT- age appropriate Transitions (age appropriate) Milestones training (age appropriate)	Other: Routine Physical Therapy; Neurodevelopmental treatment- age appropriate

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Gross Motor Function	Gross Motor Function Classification System (GMFCS) is a 5-level clinical classification system that describes the gross motor function of people with cerebral palsy on the basis of self-initiated movement abilities. Higher scores indicate better improvement in gross motor functions.	9 months

Collaborators and Investigators

• Sponsor: University of Lahore
• Investigators: Principal Investigator: Muhammad Jawad, MSPTN, The University of Lahore

Study record dates

Study Major Dates

• Study Start (Actual): December 1, 2021
• Primary Completion (Actual): May 30, 2022
• Study Completion (Actual): June 10, 2022

Study Registration Dates

• First Submitted: June 23, 2022
• First Submitted That Met QC Criteria: June 23, 2022
• First Posted (Actual): June 29, 2022

Study Record Updates

• Last Update Posted (Actual): June 29, 2022
• Last Update Submitted That Met QC Criteria: June 23, 2022
• Last Verified: June 1, 2022

More Information

Terms related to this study

• Keywords: : Spastic Quadriplegia, Cerebral palsy; Proprioceptive training, Somatosensory input
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Brain Damage, Chronic; Musculoskeletal Diseases; Muscular Diseases; Neuromuscular Manifestations; Muscle Hypertonia; Cerebral Palsy; Muscle Spasticity
• Other Study ID Numbers: IRB-UOL-FAHS/831-VI/2021

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No