Assessment of Respiratory Function Cerebral Palsy Using Plyometric Exercise Sensorimotor Program

Assessment of Respiratory Function in Children With Cerebral Palsy Using Combined Plyometric Exercise and Sensorimotor Program: A Randomized Controlled Trial

To examine if adding plyometric exercises to sensorimotor exercises would improve respiratory function in children and adolescents with cerebral palsy

Study Overview

• Status: Not yet recruiting
• Conditions: Cerebral Palsy
• Intervention / Treatment: Other: Sensorimotor program and plyometric exercise

Detailed Description

Cerebral palsy (CP) is a varied group of developmental disorders secondary to a static immature brain injury that primarily results in persistent nonspecific impairment of movement and posture. Approximately 25% of all CP cases experience disturbance of motor function with unilateral spasticity pertaining to the upper and lower extremities contralateral to the affected cerebral hemisphere and categorized as spastic hemiplegia. Some asymmetries might be noted when hemiplegic children are attempting to perform motor activities. In supported standing, hemiplegic children may stand preferentially on their more functional side and exhibit postural malalignments that impair the ability to transfer body weight on the affected lower extremity.

Children and adolescents with CP have poor respiratory function, secondary to the disease process. Impaired airway clearance, recurrent aspirations, chest infections, poor cough mechanism, impaired lung function, deformity of the spine and chest, and poor nutrition status influence the respiratory condition of children and adults with CP resulting in reduced lung capacity in these individuals.

Plyometric exercises are a specific pattern of resistive strength training in which the muscle starts to contract eccentrically followed by rapid concentric contraction of the same muscle. It can jointly generate high velocity dynamic movements and high-impact force on the muscles and bones. Currently, a limited number of studies have analysed the efficacy of the plyometric training on respiratory function in children with CP or any other disabling health conditions. Preliminary studies have demonstrated the positive effect of plyometric exercises for the gross motor function in boys with unilateral CP.

• Study Type: Interventional
• Enrollment (Anticipated): 40
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Mohamed Abo-El-Ros, Ph.D; Phone Number: +201206530584; Email: maboelroose@ecu.edu.eg
• Study Contact Backup: Name: Marian Fayez, Ph.D; Phone Number: +201222748287; Email: mfayez@ecu.edu.eg

Study Locations

• Egypt
  • Giza, Egypt, 12613
    • Cairo University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 8 years to 14 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Age will be 8 - 14 years.
• children will be assigned to the study are suffering from spastic hemiplegic cerebral palsy (less than grade 1+ om Modified Ashwar Scale)
• Considering the physical problems, children will be chosen according to Growth Motor Function Classification System (GMFCS) with levels I-III
• The ability to understand simple verbal instructions.

Exclusion Criteria:

• Visual and hearing impairment; surgery within the last three months preventing them from taking part in sensorimotor physical therapy
• Severe oromotor issues
• Severe chest infections

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: study group 1; Study group A: will receive combined plyometric exercises and sensorimotor program	Other: Sensorimotor program and plyometric exercise; Children in study group A will receive combined plyometric exercises (vertical paradigm) and sensorimotor program - Children of the study group B will receive sensorimotor program alone.
Experimental: study group 2; Study group B: will receive sensorimotor program alone	Other: Sensorimotor program and plyometric exercise; Children in study group A will receive combined plyometric exercises (vertical paradigm) and sensorimotor program - Children of the study group B will receive sensorimotor program alone.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
change of spasticity	will be measured by modified Ashower Scale	six weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
change of Respiratory capacity and vital capacity	will be measured by incentive spirometry	six weeks

Collaborators and Investigators

• Sponsor: Egyptian Chinese University
• Investigators: Study Director: Eman Abdel-Halim, Cairo University

Study record dates

Study Major Dates

• Study Start (Anticipated): September 1, 2022
• Primary Completion (Anticipated): October 1, 2022
• Study Completion (Anticipated): January 1, 2023

Study Registration Dates

• First Submitted: August 15, 2022
• First Submitted That Met QC Criteria: August 17, 2022
• First Posted (Actual): August 18, 2022

Study Record Updates

• Last Update Posted (Actual): August 18, 2022
• Last Update Submitted That Met QC Criteria: August 17, 2022
• Last Verified: August 1, 2022

More Information

Terms related to this study

• Keywords: cerebral palsy; respiratory capacity; plyometric exercise
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Brain Damage, Chronic; Cerebral Palsy; Paralysis
• Other Study ID Numbers: P.T.REC/012/003787

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No