A Study of Physiologic Changes in a Telemetry Unit

September 29, 2025 updated by: Antonio J. Forte, Mayo Clinic

Physiologic Changes Associated With Health Deterioration, Medications and Fluids Used in the Telemetry Unit

The purpose of this study is to determine the physiological changes associated with health deterioration, as well as different types, doses, and routes of administration of medications and fluids in acutely ill patients.

Study Overview

Status

Enrolling by invitation

Conditions

Study Type

Observational

Enrollment (Estimated)

500

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Florida
      • Jacksonville, Florida, United States, 32224
        • Mayo Clinic Florida

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adult patients (18-65 years) admitted to the telemetry unit at Mayo Clinic Florida's Hospital with acute illness followed from admission to discharge.

Description

Inclusion Criteria: Mayo Clinic patients who:

  • Admitted to telemetry unit
  • With acute illness
  • Received any type of medication via any route of administration (oral, sublingual, intranasal, inhalational, intramuscular, intravenous, subcutaneous, transdermal)
  • Received any amount of any type of intravenous fluids
  • Cognitively and/or physically be able to sign consent

Exclusion Criteria:

- None

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in Heart Rate
Time Frame: Baseline, through telemetry unit stay (approximately 1-3 days)
Number of beats per minute
Baseline, through telemetry unit stay (approximately 1-3 days)
Change in Blood Pressure
Time Frame: Baseline, through telemetry unit stay (approximately 1-3 days)
Measured in millimeters of mercury (mmHg)
Baseline, through telemetry unit stay (approximately 1-3 days)
Change in Respiratory Rate
Time Frame: Baseline, through telemetry unit stay (approximately 1-3 days)
Number of breaths per minute
Baseline, through telemetry unit stay (approximately 1-3 days)
Change in Oxygen Saturation Levels
Time Frame: Baseline, through telemetry unit stay (approximately 1-3 days)
Measured by a pulse oximeter reading reported as a percentage
Baseline, through telemetry unit stay (approximately 1-3 days)
Change in ECG morphology
Time Frame: Baseline, through telemetry unit stay (approximately 1-3 days)
Changes in ECG waveform appearance measured from the digital ECG waveform interpretation
Baseline, through telemetry unit stay (approximately 1-3 days)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mayo Clinic

Investigators

  • Principal Investigator: Antonio Forte, MD, PhD, Mayo Clinic

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 22, 2023

Primary Completion (Estimated)

August 1, 2026

Study Completion (Estimated)

August 1, 2027

Study Registration Dates

First Submitted

September 6, 2022

First Submitted That Met QC Criteria

September 8, 2022

First Posted (Actual)

September 9, 2022

Study Record Updates

Last Update Posted (Estimated)

October 1, 2025

Last Update Submitted That Met QC Criteria

September 29, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • 22-006064

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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