Effects of Eccentric Potentiation Activation on Muscle Function

Effects of Multi-joint Eccentric Potentiation Maximal Contractions on Muscle Function

The purpose of this study is to examine the potentiation effects of 2 sets of multi-joint eccentric overload maximal contractions on muscle function.

Study Overview

• Status: Withdrawn
• Conditions: Post Activation Potentiation
• Intervention / Treatment: Other: Cycle ergometer; Other: Eccentric Exercise

• Study Type: Interventional
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Brennan J Thompson, PhD; Phone Number: 435-881-0363; Email: brennan.thompson@usu.edu
• Study Contact Backup: Name: Sara Harper, PhD; Phone Number: 435-797-1376; Email: sara.harper@usu.edu

Study Locations

• United States
  • Utah
    • Logan, Utah, United States, 84322
      • Utah State University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 16 years to 28 years (Adult)
• Accepts Healthy Volunteers: Yes

Description

Exclusion Criteria:

• lower body surgery or injury in the last 12 months
• have any neuromuscular disease
• height >76 inches tall
• height <54 inches tall
• eccentric strength greater than 725 pounds
• pregnant or plan to be pregnant in the duration of the protocol
• don't do resistance exercise at least once per week
• perform intense cardio or strength training >4 days per week
• Present with any other significant comorbid conditions that would impair the ability to participate in the exercise-based testing

Inclusion criteria:

• 18 - 30 years old
• strength train lower body 1-3 times per week

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Cycling exercise; Cycling on a cycle ergometer instead of doing the experimental eccentric exercise.	Other: Cycle ergometer; Individuals will do a randomized crossover intervention involving cycling (active control) exercise
Experimental: Eccentric exercise; Perform 2 sets of maximal eccentric contractions as the single session exercise intervention.	Other: Eccentric Exercise; Individuals will do a randomized crossover intervention involving maximal eccentric contractions (2 sets of 6 per leg; experimental condition)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Vertical Jump	3 countermovement vertical jumps, with 30 seconds of rest between attempts	Baseline (pretest)
Vertical Jump	3 countermovement vertical jumps, with 30 seconds of rest between attempts	Immediately post intervention
Vertical Jump	3 countermovement vertical jumps, with 30 seconds of rest between attempts	12 minutes post intervention
Vertical Jump	3 countermovement vertical jumps, with 30 seconds of rest between attempts	20 minutes post intervention
Isokinetic eccentric maximal strength	Maximal eccentric strength on the Eccentron machine. 2 repetitions per time point	Baseline (pretest)
Isokinetic eccentric maximal strength	Maximal eccentric strength on the Eccentron machine. 2 repetitions per time point	Immediately post intervention
Isokinetic eccentric maximal strength	Maximal eccentric strength on the Eccentron machine. 2 repetitions per time point	12 minutes post intervention
Isokinetic eccentric maximal strength	Maximal eccentric strength on the Eccentron machine. 2 repetitions per time point	20 minutes post intervention

Collaborators and Investigators

• Sponsor: Brennan Thompson
• Investigators: Principal Investigator: Brennan J Thompson, PhD, Utah State University

Study record dates

Study Major Dates

• Study Start (Actual): November 1, 2022
• Primary Completion (Actual): March 1, 2024
• Study Completion (Actual): March 1, 2024

Study Registration Dates

• First Submitted: October 24, 2022
• First Submitted That Met QC Criteria: October 28, 2022
• First Posted (Actual): November 4, 2022

Study Record Updates

• Last Update Posted (Actual): April 23, 2024
• Last Update Submitted That Met QC Criteria: April 19, 2024
• Last Verified: April 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: 12042c

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No