Blood Flow Path Reconstruction in Rectal Cancer

Blood Flow Path Reconstruction in Rectal Cancer After High IMA Ligation Through Preoperative and Postoperative Comparison by Manual Subtraction CTA

A total of 89 patients with distal sigmoid and rectal cancer were referred for observation and underwent MS-CTA between June 2020 and March 2022. The distribution of the left colic artery (LCA) was classified, and the presence of the accessory middle colic artery (AMCA) was assessed. Blood flow paths were planned preoperatively based on the classification of LCA branches. High ligation was performed during standard radical surgery. Intraoperatively, particular care was taken to preserve the bifurcation of the ascending and descending branches of the LCA. The planned blood flow paths were then compared with the actual postoperative blood flow paths to validate the previously proposed mechanism.

Study Overview

• Status: Completed
• Conditions: Rectal Cancer; Surgery; Image
• Intervention / Treatment: Other: no intervention

• Study Type: Observational
• Enrollment (Actual): 89

Contacts and Locations

Study Locations

• China
  • Shandong
    • Jinan, Shandong, China, 250013
      • Guoqin LIU

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 39 years to 81 years (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

Patients with distal sigmoid colon or rectal cancer and they were received routine laparoscopic surgery.

Description

Inclusion Criteria:

• Clinical diagnosis of distal sigmoid colon or rectal cancer
• cTNM stage confirmed as I-III on MRI or CT
• Undergoing laparoscopic anterior resection (LAR)

Exclusion Criteria:

• Arterial phase scanning initiated too early
• Unclear anatomic structure on imaging
• No postoperative enhanced CT

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Other

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Six pattens of blood flow and AMCA based on the preoperative observation	1 hour after the manual subtraction computed tomography angiography (MS-CTA) procedure

Collaborators and Investigators

• Sponsor: Shandong First Medical University
• Collaborators: Jinan Central Hospital

Study record dates

Study Major Dates

• Study Start (Actual): June 8, 2020
• Primary Completion (Actual): March 8, 2022
• Study Completion (Actual): March 31, 2022

Study Registration Dates

• First Submitted: December 21, 2022
• First Submitted That Met QC Criteria: December 21, 2022
• First Posted (Actual): January 6, 2023

Study Record Updates

• Last Update Posted (Actual): September 22, 2025
• Last Update Submitted That Met QC Criteria: September 16, 2025
• Last Verified: December 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Neoplasms by Site; Neoplasms; Intestinal Diseases; Gastrointestinal Neoplasms; Digestive System Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colorectal Neoplasms; Intestinal Neoplasms; Rectal Diseases; Rectal Neoplasms
• Other Study ID Numbers: 2020GQliu

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: It will be available when our paper is accepted.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No