Protocol of Geriatric Rehabilitation in Patients of 60 and Older Who Live in Moscow Boarding Houses or Nursing Homes (POSTSCRIPTUM)

POSTSCRIPTUM: Protocol of Geriatric Rehabilitation in Patients of 60 and Older Who Live in Moscow Boarding Houses or Nursing Homes. Protocol of Multicentral Prospective Study.

After screening complex geriatric assessment (CGA) the participants will undergo geriatric rehabilitation programs. After termination of 21-day program, CGA will be repeated and subjects will get a program of long-term rehabilitation. A phone call in six months and a face-to-face visit in 12 months will be scheduled to follow-up and to evaluate the progress in rehabilitation.

Study Overview

• Status: Completed
• Conditions: Frail Elderly Syndrome
• Intervention / Treatment: Other: Geriatric rehabilitation program based on CGA

Detailed Description

After screening complex geriatric assessment (CGA) the participants will undergo geriatric rehabilitation programs. The participation duration will not exceed 13.5 months including the screening period.

The study comprises three periods:

• screening (1-14 days)
• a treatment course of 21 days
• a follow-up period of 12 months On screening visit Study procedures will include
• Informed consent signing
• The Comprehensive Geriatric Assessment (CGA)
• The recommendations on a program of geriatric rehabilitation based on CGA

Visit 2 will be performed at the end of rehabilitation program. It will include:

• The abbreviated CGA
• The evaluation of the results of 21-days geriatric rehabilitation program
• The recommendations on a long-term geriatric rehabilitation

Visit 3 will be scheduled in 3 months after Visit 2 as a phone call. Special questionnaire will be suggested to study subjects. The questionnaire includes questions on implementation of a geriatric rehabilitation program and on quality of life

Visit 4- the last study visit will be performed in 12 months after Visit 2. It will include CGA and study completion procedures.

• Study Type: Observational
• Enrollment (Actual): 420

Contacts and Locations

Study Locations

• Russian Federation
  • Moscow, Russian Federation, 129226
    • Russian Research and Clinical Center for Gerontology

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 60 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

men and women aged 60 years and older eligible for geriatric rehabilitation, who were addmited to one of the study sites

Description

Inclusion Criteria:

1. Men and women aged 60 and older who wanted to participate in the study and signed a consent form.

2. One or more indications for geriatric rehabilitation:

   • A discharge after a hospitalization due to an acute illness (excluding stroke and myocardial infarction), trauma, surgery, including planned ones.
   • A condition leading to an acute impairment of functional status (stress, etc.)
   • Newly admitted patients
   • Abnormalities of gait and mobility (R26)

Exclusion Criteria:

1. One or more contraindications to geriatric rehabilitation:

   1. Severe sensory and cognitive impairment hampering rehabilitation
   2. End stage diseases requiring palliative care
   3. End stage frailty (bedridden patients)
2. An acute illness or an exacerbation of a chronic disease during two weeks before the enrollment in the study
3. A contradiction to any component of a rehabilitation program
4. Hearing or visual lost that can influence on study tests results
5. Refuse to participate in the study -

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Frail elderly subjects; Frail subjects of 60 years and older will get geriatric rehabilitation program based on CGA	Other: Geriatric rehabilitation program based on CGA; Geriatric rehabilitation program based on CGA will be performed under physicians tight control for 21 days and will include physical activity, psychological training, diet correction, adaptation measures, polypragmasia correction.
Pre-Frail elderly subjects; Pre-Frail subjects of 60 years and older will get geriatric rehabilitation program based on CGA	Other: Geriatric rehabilitation program based on CGA; Geriatric rehabilitation program based on CGA will be performed under physicians tight control for 21 days and will include physical activity, psychological training, diet correction, adaptation measures, polypragmasia correction.
Non-frail elderly Frail subjects; Non-frail Frail subjects of 60 years and older will get geriatric rehabilitation program based on CGA	Other: Geriatric rehabilitation program based on CGA; Geriatric rehabilitation program based on CGA will be performed under physicians tight control for 21 days and will include physical activity, psychological training, diet correction, adaptation measures, polypragmasia correction.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
functional status dynamics	Instrumental Activity Daily Life scale score	13 months

Collaborators and Investigators

• Sponsor: Pirogov Russian National Research Medical University
• Investigators: Principal Investigator: Olga N Tkacheva, Dr., - Pirogov Russian National Research Medical University, the Russian Research and Clinical Center for Gerontology

Study record dates

Study Major Dates

• Study Start (Actual): August 21, 2021
• Primary Completion (Actual): August 31, 2023
• Study Completion (Actual): August 31, 2024

Study Registration Dates

• First Submitted: February 13, 2023
• First Submitted That Met QC Criteria: February 13, 2023
• First Posted (Actual): February 23, 2023

Study Record Updates

• Last Update Posted (Actual): June 13, 2025
• Last Update Submitted That Met QC Criteria: June 11, 2025
• Last Verified: May 1, 2025

More Information

Terms related to this study

• Keywords: frailty; elderly; geriatric rehabilitation; Complex geriatric assessment
• Other Study ID Numbers: 2021/GR

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No