Effects of Dual-Task Training In Individuals With Alzheimer

November 18, 2025 updated by: Mehmet Ozkeskin, Ege University

Effects Of Dual-Task Training On Balance, Fear Of Falling,Cognitive Functions, Dual-Task Performance, Depression And Quality Of Life In Individuals With Alzheimer

The purpose of this study is to investigate the effects of dual-task training on balance, fear of falling, cognitive functions, dual-task performance, depression and quality of life in individuals with Alzheimer.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Eligible participants will be randomized to control or dual-task training group.Control group will receive conventional therapy generally consisted of lower and upper range of motion exercises for 30 minutes 2 times a week for 8 weeks.Dual-task training group will receive exercises involving motor-cognitive dual-task exercises for 30 minutes 2 times a week for 8 weeks.Each participant will be assessed before and after the 8 weeks of treatment.

Study Type

Interventional

Enrollment (Actual)

34

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Karsıyaka
      • Izmir, Karsıyaka, Turkey (Türkiye), 35580
        • Karsiyaka Municipality Day Living Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • having been diagnosed with mild or moderate Alzheimer's disease
  • able to walk with or without assistance
  • having sufficient visual and auditory ability to perform the cognitive tests
  • being fit to perform physical exercises
  • being able to participate in proposed interventions and assessments

Exclusion Criteria:

  • having a neurological disorder other than Alzheimer
  • having any musculoskeletal problems that can affect balance
  • having any contraindication to exercise
  • functional limitation or sensory impairment that may affect performance
  • major depression

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Control Group
Participants in control group will receive an exercise program consisted of upper and lower range of motion exercises.The exercises will be started as 8-10 repetitions and 1 set and the number of sets will be increased according to the progression of the patient. Exercises will be applied for 8 weeks, 2 days a week, each session will last for 30 minutes.
Other: Control Group
Upper and lower extremity range of motion exercises will be applied for 8-10 repetitions for 1 set 2 times a week for 8 weeks.
Experimental: Dual-Task Training Group
Participants in the dual-task training group will receive exercises involving both motor and cognitive functions.Dual-task training sessions will begin with 10 minutes of stretching and proceed with 20 minutes of motor-cognitive dual-task exercises (counting backwards from 30 on double stance, naming the months and singing when standing on soft surfaces, finding words that starts with a given letter etc.) and sessions will end with 10 minutes of cooling.Exercises will be applied for 8 weeks 2 days a week each session will last for 30 minutes.
Other: Dual-Task Training
Motor-cognitive dual-task exercises will be applied for 2 days a week for 8 weeks.Sessions will last for 30 minutes.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Timed Up And Go(TUG)
Time Frame: eight weeks
It is a frequently used test that evaluates functional mobility and dynamic balance. At the beginning of the test, individuals sit in a chair. A distance of 3 m is set in front of the patient. With the start command, the patient gets up from his seat and walks 3 m, turns around and walks back and sits. With the start command, the time until the moment of sitting on the chair is recorded in seconds.Shorter duration indicates better functional mobility.
eight weeks
5 Times Sit To Stand Test(5XSST)
Time Frame: eight weeks
5XSST evaluates lower extremity functional strength, transitional movements, balance and fall risk. The time it takes for the participant to sit and get up from a chair 5 times is recorded in seconds. Interpretations are made about balance and fall risk by comparing the norm times for age with the time the individual completes the test.
eight weeks
Cognitive Reserve Index Questionaire(CRIq)
Time Frame: eight weeks
CRIq assesses an individual's cognitive reserve through compiling information about their entire adult life. If the participant has a suspected or confirmed cognitive weakness, the questionnaire must be answered by a family member or caregiver. The total score is obtained by recording the frequency of the individual's educational life, work and leisure activities in years. According to the score, the participant's cognitive reserve is interpreted as low, low - medium, medium, medium - high or high
eight weeks
Quality of Life in Alzheimer's Disease(QOL-AD)
Time Frame: eight weeks
There are two versions of the scale: patient and family member/caregiver. In order to maximize construct validity, the scale is filled in independently by both patients and caregivers. It consists of questions asked about different aspects of life in order to determine the quality of life of the person. For each question, they are asked to choose the most appropriate one from the Poor, Fair, Good or Excellent answers.Higher scores indicate better quality of life.
eight weeks
Geriatric Depression Scale(GDS)
Time Frame: eight weeks
The scale consists of 30 questions questioning how the participant felt in the past week. The person is asked to give the appropriate Yes(0) or No(1) answer to each question.Scores higher than 5 indicate depression.
eight weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Dual-Task Questionnaire(DTQ)
Time Frame: eight weeks
The Dual Task Questionnaire assesses the frequency of difficulties experienced by individuals with neurological injury or disease during activities of daily living that involve dual tasks. DTQ is scored between 0-40. Higher scores indicate more frequent dual-task difficulties.
eight weeks
Modified Falling Efficacy Scale(MFES)
Time Frame: eight weeks
The scale consists of 14 items. On a scale of 0 to 10 (on the scale), the participant asked how safe they feel doing each of these activities without falling, with 0 being "not safe/not sure", 5 "quite safe/quite confident", and 10 "completely safe/ are asked to rate it in terms of being completely sure.
eight weeks
Mini Mental Test(MMT)
Time Frame: eight weeks
Scoring is made between 0-30 on the scale in which the sub-headings of orientation, recording memory, attention and calculation, recall, language are evaluated.Lesser scores indicate worse cognitive function.
eight weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ege University

Investigators

  • Study Chair: Sevnaz ŞAHIN, PhD, Ege University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 15, 2023

Primary Completion (Actual)

December 15, 2023

Study Completion (Actual)

April 15, 2024

Study Registration Dates

First Submitted

March 1, 2023

First Submitted That Met QC Criteria

March 1, 2023

First Posted (Actual)

March 13, 2023

Study Record Updates

Last Update Posted (Actual)

November 20, 2025

Last Update Submitted That Met QC Criteria

November 18, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MOzkeskin874

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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