Digital Youth-Nominated Support Team (YST) Program

An Open-Label Study of the Feasibility and Usability of a Digital Psychoeducational Social Network Intervention for Suicidal Adolescents

The Electronic Youth-Nominated Support Team (eYST), is experimental. The purpose of this study is to get feedback from users about eYST. Another purpose of this study is to learn how well eYST helps youth.

Study Overview

• Status: Completed
• Conditions: Suicide
• Intervention / Treatment: Behavioral: eYST website

Detailed Description

Assessment data from multiple stakeholders (i.e., youth, parents, and support adults) will be collected at baseline, 4 weeks, 8 weeks, and 12 weeks via self-report and semi-structured interviews.

A request to extend the record's NIH results reporting deadline to November 1, 2025 was submitted in a timely manner prior to October-November 2025 government shutdown. This request was approved retroactively once the shutdown ended on November 12. During the shutdown, the record was locked and could not be edited by the Responsible Party. Results were submitted as soon as possible upon the unlocking of the record.

• Study Type: Interventional
• Enrollment (Actual): 75
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Michigan
    • Ann Arbor, Michigan, United States, 48109
      • Michigan Medicine

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

1. Inpatient psychiatric patients who have attempted suicide or have documented Suicide ideation (SI) and a plan to harm themselves at admission.
2. Understand written and spoken English.
3. Own a smartphone or mobile phone.
4. Willing and able to complete enrollment procedures.
5. Parent or guardian and youth able to understand the nature of the study and provide written informed consent and assent for youth
6. Patients who are able to provide at least one verifiable contact for emergency or tracking purposes.

Exclusion Criteria:

1. Patients with active psychosis.
2. Patients experiencing substance withdrawal.
3. Currently enrolled in other treatment studies for the symptoms and behaviors targeted.
4. Patient unwilling or unable to wear a mask during in person study procedures, if mandated due to current COVID/health safety guidelines.
5. Patients who in the judgment of the investigator would have an unfavorable risk or benefit profile with respect to eYST.
6. Any other psychiatric or medical condition or custody arrangement that in the investigators' opinion would preclude informed consent or assent or participation in the trial.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: eYST website	Behavioral: eYST website; The website is a psychoeducational, social support program for adolescents at risk for suicide

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
System Usability Scale (SUS) Score - Youth Participants	10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Youth Participants.	At 4 Weeks
System Usability Scale (SUS) Score - Adult Caregiver Participants	10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Adult Caregiver Participants.	At 4 Weeks
System Usability Scale (SUS) Score - Adult Support Participants	10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Adult Support Participants.	At 8 Weeks
Frequency of Use of App - Youth Participants	Website usage metrics were captured by counting the number of website log-ins by Youth (adolescent) Participants.	Weeks 1, 4, 8, and 12
Frequency of Use of App - Adult Caregiver Participants	Website usage metrics were captured by counting the number of website log-ins by parents/caregivers.	Weeks 1, 4, 8, and 12
Frequency of Use of App - Adult Support Participants	Website usage metrics were captured by counting the number of website log-ins by supporting adults.	Week 1, 4, 8, 12
Duration of Use of App - Youth Participants	Website usage metrics were captured by measuring the duration of website use by adolescents.	Weeks 1, 4, 8, and 12
Duration of Use of App - Adult Caregiver Participants	Website usage metrics were captured by measuring the duration of website use by parents/caregivers.	Weeks 1, 4, 8, and 12
Duration of Use of App - Adult Support Participants	Website usage metrics were captured by measuring the duration of website use by by support adults.	Weeks 1, 4, 8, and 12

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Feasibility of Intervention Measure (FIM) - Youth Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention feasibility. Results reflect data from Youth Participants.	At 4 Weeks
Feasibility of Intervention Measure (FIM) - Adult Caregiver Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention feasibility. Results reflect data from Adult Caregiver Participants.	At 4 Weeks
Feasibility of Intervention Measure (FIM) - Adult Support Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention feasibility. Results reflect data from Adult Support Participants.	At 8 Weeks
Acceptability of Intervention Measure (AIM) - Youth Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher acceptability. Results reflect data from Youth Participants.	At 4 Weeks
Acceptability of Intervention Measure (AIM) - Adult Caregiver Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher acceptability. Results reflect data from Adult Caregiver Participants.	At 4 Weeks
Acceptability of Intervention Measure (AIM) - Adult Support Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher acceptability. Results reflect data from Adult Support Participants.	At 8 Weeks
Intervention Appropriateness Measure (IAM) - Youth Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention appropriateness. Results reflect data from Youth Participants.	At 4 Weeks
Intervention Appropriateness Measure (IAM) - Adult Caregiver Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention appropriateness. Results reflect data from Adult Caregiver Participants.	At 4 Weeks
Intervention Appropriateness Measure (IAM) - Adult Support Participants	Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention appropriateness. Results reflect data from Adult Support Participants.	At 8 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Youth Participants	The CSQ-I was a valid and reliable scale for measuring overall satisfaction with health and human services, including digital or internet-based intervention. This was adapted for use with youth, parents, and support adults. The adapted scales each had 8 items in a Likert scale ranging from 8-32 where higher numbers indicated higher satisfaction. Results reflect data from Youth Participants.	At 4 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Adult Caregiver Participants	The CSQ-I was a valid and reliable scale for measuring overall satisfaction with health and human services, including digital or internet-based intervention. This was adapted for use with youth, parents, and support adults. The adapted scales each had 8 items in a Likert scale ranging from 8-32 where higher numbers indicated higher satisfaction. Results reflect data from Adult Caregiver Participants.	At 4 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Adult Support Participants	The CSQ-I was a valid and reliable scale for measuring overall satisfaction with health and human services, including digital or internet-based intervention. This was adapted for use with youth, parents, and support adults. The adapted scales each had 8 items in a Likert scale ranging from 8-32 where higher numbers indicated higher satisfaction. Results reflect data from Adult Support Participants.	At 8 Weeks

Collaborators and Investigators

• Sponsor: University of Michigan
• Collaborators: National Institute of Mental Health (NIMH)
• Investigators: Principal Investigator: Alejandra Arango, University of Michigan; Study Director: Patricia Simon, Oui Therapeutics, Inc.

Study record dates

Study Major Dates

• Study Start (Actual): November 27, 2023
• Primary Completion (Actual): September 30, 2024
• Study Completion (Actual): September 30, 2024

Study Registration Dates

• First Submitted: June 2, 2023
• First Submitted That Met QC Criteria: June 2, 2023
• First Posted (Actual): June 12, 2023

Study Record Updates

• Last Update Posted (Actual): March 18, 2026
• Last Update Submitted That Met QC Criteria: March 16, 2026
• Last Verified: March 1, 2026

More Information

Terms related to this study

• Keywords: Website; Social network
• Additional Relevant MeSH Terms: Behavioral Symptoms; Self-Injurious Behavior; Behavior; Suicide
• Other Study ID Numbers: HUM00221931; 5R43MH128431-02 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No