A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

March 10, 2025 updated by: Qing-he Zhou, Affiliated Hospital of Jiaxing University
The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Study Overview

Status

Completed

Conditions

Detailed Description

  1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV
  2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed.
  3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Study Type

Observational

Enrollment (Actual)

64

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Zhejiang
      • Jiaxing, Zhejiang, China, 314000
        • Affiliated Hospital of Jiaxing University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

Patients undergoing intravenous general anesthesia surgery at Jiaxing First Hospital

Description

Inclusion Criteria:

  • age over 60 years
  • American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ
  • Surgery with radial artery puncture
  • Propofol induction

Exclusion Criteria:

  • BMI≥30kg/m2
  • People with short necks;
  • Previous hypotension (systolic blood pressure <90mmHg or mean arterial pressure <65mmHg)
  • Previous poorly controlled hypertension
  • Cardiac insufficiency , EF value<50%
  • Upper limb deep vein thrombosis
  • History of radiotherapy or neck surgery
  • Inability to maintain a supine position for necessary measurements
  • Mechanical ventilation status or inability to take deep breaths patients
  • gastrointestinal surgery
  • patients allergic to propofol.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
IJVV during deep inhalation
Time Frame: 1 year
IJVV (%) = (diamax - diamin)/[(diamax + diamin)/2] × 100
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Affiliated Hospital of Jiaxing University

Investigators

  • Principal Investigator: Qinghe Zhou, Affiliated Hospital of Jiaxing University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 29, 2023

Primary Completion (Actual)

January 31, 2024

Study Completion (Actual)

January 31, 2024

Study Registration Dates

First Submitted

October 29, 2023

First Submitted That Met QC Criteria

October 29, 2023

First Posted (Actual)

November 1, 2023

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

March 10, 2025

Last Verified

March 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2023-KY-603

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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