Neuromuscular Training Program in Patients With Knee OA (Osteoarthritis) (OA)

Comparison of the Effectiveness of Neuromuscular Training Program and Conventional Physical Therapy Program in Patients With Knee Osteoarthritis.

The aim of this study was to compare the effects of neuromuscular training program and conventional physical therapy program on pain, functional status, physical performance, balance, muscle strength and quality of life in patients with knee osteoarthritis (KOA).

Study Overview

• Status: Completed
• Conditions: Knee Osteoarthritis
• Intervention / Treatment: Other: Neuromuscular training program; Other: conventional physical therapy program

Detailed Description

The study was carried out in Afyonkarahisar Health Sciences University Health Application Research Center in individuals with 2nd or 3rd degree KOA according to Kellgren and Lawrence Classification. The study was planned as a randomized controlled clinical trial design. The study group were recruited to the neuromuscular training program and the control group were recruited to the conventional physical therapy program 5 days a week for 3 weeks. Individuals were evaluated at the baseline and after training programs. Demographic and clinical data were first recorded in the evaluation.

• Study Type: Interventional
• Enrollment (Actual): 70
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Kütahya, Turkey, 43100
    • Kutahya Health Science University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Having grade 2 or 3 osteoarthritis according to the Kellgren and Lawrence Classification
• Having pain score of 2 or above on VAS
• Not having received physical therapy in the last 3 months
• Not having received an intra-articular corticosteroid injection in the last 6 months
• Not having used oral corticosteroids in the last month
• Being between the ages of 40-80
• Body mass index being between 19-40 kg/cm2

Exclusion Criteria:

• Systemic arthritis
• Hypertensive condition that prevents exercise
• Pregnancy, cognitive impairment, parkinson-like neurological disorders
• Having had a knee or hip joint replacement

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: neuromuscular training program; Participants were administered the neuromuscular training program 60 min a day, 2 days a week for 8 weeks.	Other: Neuromuscular training program; Hotpack application TENS (transcutaneous electrical stimulation) Warm-up phase: bicycle ergometer (ten minutes) Exercise phase: core stabilization and postural control exercises postural orientation exercises lower extremity strengthening exercises functional exercises (balance and proprioception exercises using a balance board) Cool-down Phase
Active Comparator: conventional physical therapy program; Participants were administered the conventional physiotherapy program 60 min a day, 2 days a week for 8 weeks.	Other: conventional physical therapy program; Hotpack application TENS (transcutaneous electrical stimulation) Conventional physical therapy exercises (straight leg raises, knee flexor and extensor strengthening, hip muscle strengthening)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Visual Analog Scale	Pain evaluation. The participant is asked to give a score between 1 and 10 for her pain.	At first and third week
Western Ontario and McMasterUniversities Osteoarhritis Index	Functional status evaluation. The scale consists of 3 subheadings that evaluate pain, stiffness and physical function. High Western Ontario and McMasterUniversities Osteoarhritis Index score indicates increased pain and stiffness and deterioration in physical function.	At first and third week
Time on One Leg Standing	Balance evaluation. Participants were asked to stand on one leg with their eyes open for as long as possible, and the time was measured with a stopwatch and recorded in seconds.	At first and third week
Five Times Sit to Stand Test	Physical performance evaluation. The time it takes for the patient to sit and stand up from a chair five times is recorded. As time decreases, it indicates better performance.	At first and third week
Manual Muscle Test	Muscle strength evaluation. A score between 0 and 5 is given depending on muscle strength.	At first and third week
Short Form	Quality of life evaluation. It consists of 8 subheadings: physical function, problems caused by physical problems, emotional well-being, problems caused by emotional problems, general health, social function, pain, energy/fatigue. High scores indicate good health, low scores indicate poor health.	At first and third week

Collaborators and Investigators

• Sponsor: Kutahya Health Sciences University

Study record dates

Study Major Dates

• Study Start (Actual): January 15, 2022
• Primary Completion (Actual): January 15, 2023
• Study Completion (Actual): June 15, 2023

Study Registration Dates

• First Submitted: February 10, 2024
• First Submitted That Met QC Criteria: February 20, 2024
• First Posted (Estimated): February 21, 2024

Study Record Updates

• Last Update Posted (Estimated): February 21, 2024
• Last Update Submitted That Met QC Criteria: February 20, 2024
• Last Verified: February 1, 2024

More Information

Terms related to this study

• Keywords: Knee osteoarthritis; Physical therapy; Neuromuscular training
• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis; Osteoarthritis, Knee
• Other Study ID Numbers: NMTwithKOA

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: There is not a plan to make IPD available.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No