Compensatory and Restorative Rehabilitation Techniques in Stroke (The)

September 1, 2025 updated by: Riphah International University

Combined Effects of Restorative and Compensatory Rehabilitation Techniques on Executive Functions in Stroke With Mild Cognitive Impairment

The aim of this randomized controlled trial is to find the combined effects of restorative and compensatory cognitive rehabilitation techniques in mild cognitive impairment after stroke.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Stroke is a prevalent medical neurological condition that often results in cognitive impairments, particularly in the domain of executive functions. Cognitive impairment has a significant impact on executive function in stroke subjects. Cognitive impairment on the stroke survivor exist on any single domain such as attention, spatial ability, language and executive ability more frequently than the multiple domains.

Cognitive training has been shown to be beneficial for rehabilitation of patients with cognitive impairment, but the underlying mechanisms remain unclear.

The combination of restorative and compensatory rehabilitation techniques is beneficial for gaining control over cognitive rehabilitation techniques will improve executive functions. The retention effects evaluated additionally will add a broad insight in this regard. It will improve the learning power of brain through neural plasticity. This leads to restoration of everyday functioning. This study aims to investigate the effects of two distinct rehabilitation approaches on the executive functions of stroke survivors with MCI. Understanding how these rehabilitation strategies impact cognitive recovery is essential for individuals living with post-stroke cognitive impairments.

Study Type

Interventional

Enrollment (Actual)

36

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Pakistan
    • Punjab Province
      • Dina, Punjab Province, Pakistan
        • Shafi Hospital Dina

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Age between 50 and 70 years
  • Both Genders
  • Individuals diagnosed with stroke 6 months before enrollment
  • Minimum 6 years of schooling
  • Patients with mild cognitive impairment (score 18-25 on MOCA)
  • Individuals able to maintain sitting and standing balance (score 41 on berg balance scale)

Exclusion Criteria:

  • >10 on post stroke depression rating scale (PSDRS)
  • Spasticity (>3 on Ashworth scale)
  • Other psychological disorders
  • Patients diagnosed with Alzheimer's and dementia

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Compensatory and restorative rehabilitation techniques
compensatory and restorative rehabilitation techniques in stroke patients
Other: compensatory and restorative rehabilitation techniques

compensatory and restorative rehabilitation techniques Frequency: 10 reps 2-3 times/week for 3 consecutive weeks then evaluation of the effects.

Continue the same techniques for 3 more weeks and then evaluate the retention effects of restorative and compensatory rehabilitation techniques will be evaluated by 9th week.
Active Comparator: Traditional cognitive Rehabilitation training
Naming words Counting numbers backwards Spell the word backwards
Other: Traditional cognitive rehabilitation training

Naming words ( ask patient to name food, states, family members) Counting numbers backwards, backward counting of days and months) Spell the word backwards, remembering a piece of information Frequency: 10 reps 2-3 times/week for 3 consecutive weeks then evaluation of the effects.

Continue the same techniques for 3 more weeks and then evaluate the retention effects of restorative and compensatory rehabilitation techniques will be evaluated by 9th week.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Montreal cognitive assessment test (Urdu version)
Time Frame: 6 weeks
MOCA assesses different cognitive domains: attention and concentration, executive functions, memory, language, visuo-constructional skills, conceptual thinking and orientation. The test is one page,30 point test that can be administered in 10 minutes. MOCA is scored by obtaining an item total and the author recommend a clinical cutoff score of 26.is a Patient-completed, condition-specific functional status questionnaire with 10 items including pain, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation.
6 weeks
Cognitive assessment scale for stroke patients (CASP)
Time Frame: 6 weeks
Its a rapid test for screening post stroke cognitive impairment. It can be performed at the patient bedside by a non expert examiner. A CASP score of 35/36 should alert to possible presence of cognitive impairment. Score can help predict medium level cognitive impairment.
6 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Stroke specific quality of life questionnaire (Urdu version)
Time Frame: 6 weeks
The SS-QOL questionnaire assesses health related quality of life specific to stroke survivors covering almost 12 domains
6 weeks
Modified Rankin Scale (MRS)
Time Frame: 6 weeks
It measures degree of disability or dependence in daily activities of people who have suffered stroke or other neurological disability. It is one of the most widely used clinical patients are graded
6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Aroosa Tariq, MS-NMPT, Riphah International University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 16, 2024

Primary Completion (Actual)

August 28, 2025

Study Completion (Actual)

August 29, 2025

Study Registration Dates

First Submitted

March 17, 2024

First Submitted That Met QC Criteria

March 17, 2024

First Posted (Actual)

March 22, 2024

Study Record Updates

Last Update Posted (Estimated)

September 3, 2025

Last Update Submitted That Met QC Criteria

September 1, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Ayesha Saddiqa

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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