PREVAIL Interdisciplinary Track: A Pragmatic Randomized Clinical Trial

February 13, 2026 updated by: Rena E. Courtney, Salem Veterans Affairs Medical Center

PREVAIL: Efficacy of a Veterans Healthcare Administration (VHA) Whole Health Interdisciplinary Pain Clinic

The goal of this clinical trial is to [primary purpose learn if a team that involves five types of pain specialists (interventional pain, psychology, pharmacy, nutrition, physical therapy) can treat chronic pain in Veterans. The main questions it aims to answer are:

  • Do patients report less pain after six months in the program?
  • Do patients report that pain gets in the way of their life less after six months in the program? The researchers will compare participants who participate in the program to those that wait for six months before participating in the program.

Participants will

  • Meet with the team of pain specialists to develop a plan to treat their pain
  • Receive calls from a coach once per month
  • Return to meet with the team of pain specialists for a six-month follow-up appointment
  • Fill out surveys

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

150

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • United States
    • Virginia
      • Salem, Virginia, United States, 24153
        • Recruiting
        • Salem VA Health Care System
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Veteran receiving care at the Salem VA Health Care System (Salem VAHCS) per electronic medical record (EMR)
  • Patient participating in PREVAIL Interdisciplinary Team Track per EMR
  • Chronic Pain Diagnosis: Defined as pain lasting more than three months per EMR

Exclusion Criteria:

  • Diagnosis of Mild Neurocognitive Disorder or Major Neurocognitive Disorder based on Diagnostic Statistical Manual of Mental Disorders, 5th edition, Text Revision (DSM-5-TR) per EMR
  • Veteran has a current acute physical injury that would artificially elevate pain scores during study period per EMR
  • Veteran intends to have a pain-related surgery during the study period per EMR

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Interdisciplinary Team
Participants complete surveys, meet with five pain specialists to develop individualized treatment plans based on whole health, receive monthly coaching calls for five months, then meet with the pain specialists once more for a 6-month follow-up appointment and complete surveys.
Behavioral: PREVAIL Interdisciplinary Team
Patient meets simultaneously with an interdisciplinary team (IDT) five pain specialists and develops an individualized treatment plan based on Whole Health. Participants receive five months of coaching calls then return six months later for a follow-up visit with the IDT.
No Intervention: Waitlist Control
Participants complete surveys but do not engage with the pain specialists for 6 months.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Brief Pain Inventory (BPI)
Time Frame: Baseline, 6-months
A 9-item scale used to quantify an individual's pain experience (0-10) with higher scores suggesting worse pain severity and pain interference.
Baseline, 6-months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Short Form-36 Item (SF-36)
Time Frame: Baseline, 6-months
A 36-item scale to assess quality of life, including any impact of health problems on completing activities, as well as energy and emotions, with lower scores indicating a higher impact of health problems.
Baseline, 6-months
Insomnia Severity Index
Time Frame: Baseline, 6-months
A 7-item scale that assesses sleep disturbances, with higher scores reflecting more sleep difficulty.
Baseline, 6-months
Pain Self-Efficacy Questionnaire
Time Frame: Baseline, 6-months
A 10-item scale used to determine how confident an individual is in accomplishing tasks despite the pain (0=not at all confident and 6= completely confident) with higher scores denoting higher levels of pain self-efficacy.
Baseline, 6-months
University of Washington- Concerns about Pain Scale 24-item
Time Frame: Baseline, 6-months
A 24-item scale used to assess one's perception of their pain experience (1= never, 5= always), with higher scores indicating higher levels of pain catastrophizing.
Baseline, 6-months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Salem Veterans Affairs Medical Center

Collaborators

Stanford University
Durham VA Health Care System
VISN 6 MIRECC
Bedford VA Health Care System

Investigators

  • Principal Investigator: Rena E Courtney, PhD, Salem VA Health Care System

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 1, 2024

Primary Completion (Estimated)

April 1, 2026

Study Completion (Estimated)

April 1, 2026

Study Registration Dates

First Submitted

May 17, 2024

First Submitted That Met QC Criteria

May 17, 2024

First Posted (Actual)

May 23, 2024

Study Record Updates

Last Update Posted (Actual)

February 18, 2026

Last Update Submitted That Met QC Criteria

February 13, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC 0004

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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