Evaluation of Thriving, Substance Use, Mental Health, and Repeat Injury Among Participants in the THRIVE Program

Evaluation of Thriving, Substance Use, Mental Health and Repeat Injury Among Participants in the THRIVE Program

The goal of this observational study is to determine the impact of a hospital-based violence intervention program on a person's capacity to thrive and recurrent intentional injury. The aims of this study are:

1. To evaluate the impact of the HVIP on building personal capacity of youth who have experienced non-fatal violent injuries to thrive using:

   • Established measure changes in positive psychology and clinical metrics
   • A qualitative interview using thematic content analysis
2. Plot the methodology proposed to measure the impact of THRIVE on subsequent injuries using administrative data sources

Participants will complete surveys, participate in a semi-structured interview, and have their rate of recurrent intentional injury tracked over time.

Researchers will compare the rates of intentional reinjury between participants in the THRIVE program and those who present at other hospitals with similar injuries to see if there is a difference in the rate of recurrent intentional injury a 1, 5, and 10 years.

Study Overview

• Status: Not yet recruiting
• Conditions: Violence; Assault

• Study Type: Observational
• Enrollment (Estimated): 90

Contacts and Locations

• Study Contact: Name: Jennifer Dekker, MSc; Phone Number: 437-331-8644; Email: jennifer.dekker@unityhealth.to

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Youth injured by interpersonal violence who present at the emergency department of Unity Health Toronto - St. Michael's Hospital will be offered the hospital-based violence intervention program called THRIVE. THRIVE case managers connect with youth and provide supports in-hospital and in the community following discharge, providing wrap-around care with a strengths-based approach.

Description

Inclusion Criteria:

• ages 14-29
• presentation with an injury due to violence (defined as a gun shot wound, stab wound, blunt or bodily force, inflicted by someone else)
• participant in the THRIVE Program

Exclusion Criteria:

• unable to consent due to language barrier or brain injury
• sexual assault
• child abuse
• self-inflicted injury
• residence >1 hour from Toronto city limits

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To evaluate the impact of the HVIP on building personal capacity of youth who have experienced non-fatal violent injuries to thrive.	To evaluate changes in thriving, substance use, and mental health, validated measures and qualitative measures will be used. Quantitative measures collected using validated instruments will provide objective measures of change over time; while context-specific and nuanced growth will be captured through a semi-structured interview.	July 2024 - December 2025
To pilot the methodology proposed to measure the impact of THRIVE on subsequent injuries within 1 year using administrative data sources	After 1.5 years of enrolment in THRIVE, study participants will be deterministically linked. Linkage will provide a wealth of baseline characteristics (demographics, income/marginalization), injury characteristics (ICD-10 coding patterns which can be contrasted to THRIVE documentation), as well as the capacity to follow these linked patients administratively over time and identify subsequent ED presentations and admission across any hospital in Ontario.	March - Sept 2026

Collaborators and Investigators

• Sponsor: Unity Health Toronto
• Investigators: Principal Investigator: Carolyn Snider, MD, FRCPC, Unity Health Toronto

Study record dates

Study Major Dates

• Study Start (Estimated): July 1, 2024
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): July 1, 2035

Study Registration Dates

• First Submitted: June 6, 2024
• First Submitted That Met QC Criteria: June 6, 2024
• First Posted (Actual): June 13, 2024

Study Record Updates

• Last Update Posted (Actual): June 13, 2024
• Last Update Submitted That Met QC Criteria: June 6, 2024
• Last Verified: June 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Chemically-Induced Disorders; Wounds and Injuries; Substance-Related Disorders; Reinjuries
• Other Study ID Numbers: THRIVE001

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No