Third Molars Extraction and Periodontal Disease

July 24, 2024 updated by: Malpassi Chiara, Azienda Ospedaliera Universitaria Senese

Correlation Between Upper Third Molars Extraction and Upper Second Molars Periodontal Disease: a Prospective Clinical Observational Study

The aim of the study is to evaluate the changes in periodontal conditions on the distal aspect of the second maxillary molar after the extraction of the maxillary wisdom tooth. As secondary outcome patient- related and tooth-related factors will be analysed to evaluate their effects on the periodontal varibales during time.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

126

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Italy
    • Italy/SI
      • Siena, Italy/SI, Italy, 53100
        • Recruiting
        • University of Siena
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

Hospital population.

Description

Inclusion Criteria:

  • Age more than 18 years or older
  • Presence of an impacted upper wisdom tooth that need to undergo surgical extraction
  • Participants need to be able to sign and understand the informed consent and to follow the study-related procedures.

Exclusion Criteria:

  • People that have compromised general health conditions (ASA 3, 4, 5, 6)
  • Patients that assumed antibiotics in the last 6 months
  • Pregnant or breastfeeding women
  • Patients who suffer from periodontitis stage III and IV
  • Presence of a third molar with incomplete root formation is not taken into account for the surgical extraction.
  • Smoker patients

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Group A with PPD ≤ 3 mm
Procedure: Tooth extraction
Extraction of maxillary third molars
Group B with PPD ≥ 4 mm
Procedure: Tooth extraction
Extraction of maxillary third molars

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Probing Pockeet Depth (PPD)
Time Frame: Baseline, 1 month, 6 months, 12 months, 24 months
Distance between the free gingival margin and the apical location of the probe's tip.
Baseline, 1 month, 6 months, 12 months, 24 months
Bone Level (BL)
Time Frame: Baseline, 1 month, 6 months, 12 months, 24 months
Distance between the bone crest and the cemento-enamel junction (CEJ)
Baseline, 1 month, 6 months, 12 months, 24 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Type of impaction
Time Frame: Baseline
According to Archer's classification it is possible to have seven types of impaction: mesio-angular, disto-angular, bucco-angular, linguo-angular, horizontal, vertical, inverted.
Baseline
Clinical Attachment Level (CAL)
Time Frame: Baseline, 1 month, 6 months, 12 months, 24 months
Distance between the cemento-enamel junction and the apical location of the probe's tip
Baseline, 1 month, 6 months, 12 months, 24 months
Recession (REC)
Time Frame: Baseline, 1 month, 6 months, 12 months, 24 months
Distance between the free gingival margine and the cemento-enamel junction (CEJ)
Baseline, 1 month, 6 months, 12 months, 24 months
Keratinized Tissue (KT)
Time Frame: Baseline, 1 month, 6 months, 12 months, 24 months
Distance between the muco-gingival line and the free gingival margin
Baseline, 1 month, 6 months, 12 months, 24 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Azienda Ospedaliera Universitaria Senese

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 27, 2024

Primary Completion (Estimated)

March 27, 2026

Study Completion (Estimated)

September 15, 2026

Study Registration Dates

First Submitted

July 20, 2024

First Submitted That Met QC Criteria

July 24, 2024

First Posted (Actual)

July 25, 2024

Study Record Updates

Last Update Posted (Actual)

July 25, 2024

Last Update Submitted That Met QC Criteria

July 24, 2024

Last Verified

July 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 26617

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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