The Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium

September 14, 2024 updated by: Harun Tolga Duran, Amasya University

The Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium in Elderly Patient with Low Preoperative Mini-cog Score

In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The patients were preoperatively assessed for American Society of Anesthesiologists (ASA) risk by an anesthetist and age, sex and comorbidities were recorded. The Mini-cog test was applied as a cognitive screening test by the anesthesiologist in the preoperative period and the test score was recorded. Three-word memory test, clock drawing, and visual function test was performed to evaluate the patient's cognitive functions. In this test, patients were asked to memorize three words such as umbrella, sunshine, and chair at the beginning of the test.

Study Type

Observational

Enrollment (Actual)

84

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Amasya, Turkey
        • Amasya University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Patients over 60 years of age who are scheduled for laparoscopic cholecystectomy

Description

Inclusion Criteria:

  • There was a correlation between the incidence of delirium after the age of 60(10).

Exclusion Criteria:

  • Patients' age< 60 years,
  • Patients undergoing emergency cholecystectomy or did not have preoperative Mini-Cog assessment,
  • With a history of cerebrovaskuler insult that was thought to have an effect on postoperative delirium ,
  • Patients with difficulty in cooperation ,
  • Patients with hemodynamic instability(arterial blood pressure above 160/90 mmHg and below 90/60 mmHg and patients with pulse rate below 50/min and above 100/min) ,
  • Patients with previously diagnosed dementia, and those who had surgical procedures lasting more than 2 hours were excluded from the study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
group s
Patients receiving sevoflurane
Procedure: Sevoflurane
Depending on the anesthesia maintenance protocol, total intravenous anesthesia (TIVA) or sevoflurane anesthesia, patients were divided into group T (TIVA) and group S (sevoflurane).
Group p
Patients receiving propofol-based total intravenous anesthesia
Procedure: Sevoflurane
Depending on the anesthesia maintenance protocol, total intravenous anesthesia (TIVA) or sevoflurane anesthesia, patients were divided into group T (TIVA) and group S (sevoflurane).

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Group P-S
Time Frame: postoperative 0 1st 2nd hours
Incidence of postoperative delirium in patients receiving sevoflurane or propofol-based total intravenous anesthesia
postoperative 0 1st 2nd hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Amasya University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2023

Primary Completion (Actual)

October 1, 2023

Study Completion (Actual)

November 1, 2023

Study Registration Dates

First Submitted

September 12, 2024

First Submitted That Met QC Criteria

September 14, 2024

First Posted (Estimated)

September 19, 2024

Study Record Updates

Last Update Posted (Estimated)

September 19, 2024

Last Update Submitted That Met QC Criteria

September 14, 2024

Last Verified

September 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2023/11

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

IPD Plan Description

I approve the usability in multicenter studies in the study plan population

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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