Effects of Resistance-band Training and Creatine and Whey Protein

September 18, 2024 updated by: Darren Candow, University of Regina

Effects of Resistance-band Training and Nutritional Supplementation in Healthy Older Adults

The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and/or whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Sarcopenia, characterized by the age-related reduction in strength, muscle mass, and physical function, decreases the ability to perform activities of daily living. Physical inactivity and inadequate nutrition are contributing factors to the development of sarcopenia. Resistance training is a safe, viable and effective intervention which increases measures of muscle and bone mass, muscle performance (i.e., strength, endurance) and functional ability in older adults. However, older adults indicate that high costs and difficulty finding training programming and/or facilities are barriers to participating in resistance training. Home-based resistance-band training is safe, effective and serves as a viable alternative to traditional resistance training (i.e., involving free-weights and machine-based equipment). From a healthy aging perspective, resistance-band training elicits similar improvements in strength (primary indicator of sarcopenia) and functional ability compared to traditional resistance training in older adults. In addition to resistance training (involving resistance-bands), creatine and whey protein supplementations have also been shown to have favorable effects on measures of muscle, bone and functional ability in older adults. However, no study has examined the effects of resistance-band training and creatine and whey protein supplementation in older adults.

Study Type

Interventional

Enrollment (Estimated)

36

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Canada
    • Saskatchewan
      • Regina, Saskatchewan, Canada, S4S 0A2

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)

Exclusion Criteria:

  • Taking creatine monohydrate within 30 days prior to the start of the study
  • Currently ingesting whey protein
  • Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Whey Protein
Dietary supplement: Whey Protein
30 grams Whey Protein
Experimental: Creatine Whey Protein
Dietary supplement: Creatine Whey Protein
3 grams creatine + 30 grams whey protein

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Whole-body lean mass (kg)
Time Frame: baseline, week 10, week 20
Bioelectrical impedance analysis
baseline, week 10, week 20
Strength (kg)
Time Frame: baseline, week 10, week 20
1-repetition maximum leg press and chest press
baseline, week 10, week 20
Endurance (number of repetitions to fatigue)
Time Frame: baseline, week 10, week 20
Leg press and chest press
baseline, week 10, week 20
Balance (Centre of Pressure)
Time Frame: baseline, week 10, week 20
Force Plate
baseline, week 10, week 20
Hydration (kg)
Time Frame: baseline, week 10, week 20
Bioelectrical impedance analysis
baseline, week 10, week 20
Gait Speed (meters)
Time Frame: baseline, week 10, week 20
Walking distance
baseline, week 10, week 20
Muscle Hypertrophy (cm)
Time Frame: baseline, week 10, week 20
B-mode ultrasound
baseline, week 10, week 20

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Regina

Collaborators

Iovate Health Sciences International Inc

Investigators

  • Principal Investigator: Darren Candow, University of Regina

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 18, 2024

Primary Completion (Estimated)

July 1, 2025

Study Completion (Estimated)

July 1, 2025

Study Registration Dates

First Submitted

September 16, 2024

First Submitted That Met QC Criteria

September 18, 2024

First Posted (Actual)

September 23, 2024

Study Record Updates

Last Update Posted (Actual)

September 23, 2024

Last Update Submitted That Met QC Criteria

September 18, 2024

Last Verified

September 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 825

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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