Effect of Preop and Postop ESP Block on Analgesia, Hemodynamics and Patient Satisfaction in Laparoscopic Cholecystectomy

Effects of Preoperative and Postoperative Errector Spinal Plan (ESP) Block on Postoperative Analgesia Score, Hemodynamic Response and Patient Satisfaction in Patients Undergoing Laparoscopic Cholecystectomy Surgery

Erector spinae plane (ESP) block is an interfascial plane block applied to the paraspinal region, which provides effective visceral and extensive somatic analgesia by providing paravertebral spread of the administered local anesthetic to three and four vertebral levels cranial and caudal. ESP block is a new regional anesthesia method applied with ultrasound (USG) guidance to provide analgesia for various surgeries and for acute or chronic pain. The application of this block is simple and can be performed in the preoperative waiting area with light sedation or no sedation. ESP block can be applied with a single injection or as a continuous infusion by catheter placement.

Study Overview

• Status: Completed
• Conditions: Erector Spinae Plane Block
• Intervention / Treatment: Other: postop Erector spinae plane block

Detailed Description

Erector spinae plane (ESP) block is an interfascial plane block applied to the paraspinal region, which provides effective visceral and extensive somatic analgesia by providing paravertebral spread of the administered local anesthetic to three and four vertebral levels cranial and caudal. ESP block is a new regional anesthesia method applied with ultrasound (USG) guidance to provide analgesia for various surgeries and for acute or chronic pain. The application of this block is simple and can be performed in the preoperative waiting area with light sedation or no sedation. ESP block can be applied with a single injection or as a continuous infusion by catheter placement. The first report related to this block was published in 2016; the block was performed to reduce thoracic neuropathic pain in a patient with metastatic rib disease and rib fracture. So far, the block has been reported to be performed successfully in many cases, including the Nuss procedure, thoracotomies, percutaneous nephrolithotomies, ventral hernia surgeries, and even lumbar fusions.

• Study Type: Interventional
• Enrollment (Actual): 80
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Şanlıurfa, Turkey, 63100
    • Veli Fahri Pehlivan

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• According to the physical classification of the American Society of Anesthesiologists (ASA), ASA I-II group,
• between the ages of 18-65,

Exclusion Criteria:

• Patients who do not want to participate in the study;
• BMI >30,
• Patients with contraindications for ESP block,
• Uncooperative patients,
• Those with renal failure,
• Those with hepatic failure and
• ASA III-IV-V group patients

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Preop Erector spinae plane block; Patients who underwent erector spinae block before surgery	Other: postop Erector spinae plane block; Postoperative ESP block was performed as the control group
Active Comparator: postop Erector spinae plane block; Patients who underwent erector spinae block without waking the patient at the end of surgery	Other: postop Erector spinae plane block; Postoperative ESP block was performed as the control group

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
primary outcome	1. Systolic arterial pressure,	one day

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Sevondary outcome	1. Postoperative NRS (Numerical pain scale) score,	one day

Collaborators and Investigators

• Sponsor: Harran University

Study record dates

Study Major Dates

• Study Start (Actual): November 11, 2024
• Primary Completion (Actual): June 12, 2025
• Study Completion (Actual): June 25, 2025

Study Registration Dates

• First Submitted: October 25, 2024
• First Submitted That Met QC Criteria: October 31, 2024
• First Posted (Actual): November 1, 2024

Study Record Updates

• Last Update Posted (Actual): June 29, 2025
• Last Update Submitted That Met QC Criteria: June 25, 2025
• Last Verified: June 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: Sait

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No