Deep Posterior Post Gluteal Compartment Block in Total Hip Arthroplasty: Feasability and Safety (ANATH)

Effets D'un Bloc Glutéal Postérieur Profond Associé À Un PENG Bloc Dans La Prothèse Totale De Hanche

This study aims to evaluate the effectiveness of a posterior hip capsule block performed in addition to a PENG (Pericapsular Nerve Group) block for patients undergoing hip arthroplasty. The primary objective is to assess whether this combined approach provides enhanced perioperative analgesia compared to the standard analgesic protocol or the PENG block alone. Secondary outcomes will focus on opioid consumption, functional recovery, and any potential complications. By targeting both the anterior and posterior innervation pathways around the hip joint, this combined technique could improve patient comfort, decrease opioid requirements, and potentially expedite rehabilitation after hip arthroplasty.

Study Overview

• Status: Not yet recruiting
• Conditions: Total Hip Arthroplasty
• Intervention / Treatment: Procedure: Deep posterior post gluteal nerve block

• Study Type: Interventional
• Enrollment (Estimated): 35
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: YOANN ELMALEH, M.D; Phone Number: +33781330431; Email: Yoyo.elmaleh@hotmail.fr

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

All adults with total hip arthroplasty

-

Exclusion Criteria:

• Contraindication to regional anesthesia
• allergy
• refusal of the injection

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: DPPG compartment block; Deep posterior post gluteal compartment block with different volume of product 5,10 and 15 ml (local anesthetics such as naropeine 0.35%) to compare the efficiency of the block without sciatic nerve block effect	Procedure: Deep posterior post gluteal nerve block; One injection with ultrasound guidance injection of 5, 10 or 15 mL of naropeine 0.35 % Procedure : injection below the piriformis muscle in front of the head of the femur.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Sciatic nerve block	number of patients with postoperative sciatic motor or sensitory nerve block collected by clinical examination (test with hot and cold in the sciatic territory and motricity of the feet)	From enrollment to the end of treatment at 1 month

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Pain postoperative	Visual analogic pain (VAS) AT 6 hours 0 : no pain 10: maximum pain	From enrollment to the end of treatment at 1 MONTH
pain 2	Visual analogic pain (VAS) AT 12 hours 0 : no pain 10: maximum pain	From enrollment to the end of treatment at 1 MONTH
oPIOID Consumption	Opioid consumption per and postoperative until 48 hours	From enrollment to the end of treatment at 7 months
RAAC	QOR15 scale at H24 and H48 questionnaire with 15 questions from 0 to 10 (https://pqip.org.uk/FilesUploaded/Myles%20QoR-15.pdf)	From enrollment to the end of treatment at 1 MONTH
Surgical complication	Surgical postoperative complication or fall	From enrollment to the end of treatment at 1 MONTH

Collaborators and Investigators

• Sponsor: Quincy Anesthésie
• Investigators: Principal Investigator: yoann ELMALEH, M.D, Hôpital Privé Claude Galien

Publications and helpful links

General Publications

• Pun M, Ng T, Vermeylen K, Tran J. Innervation of the hip joint: implications for regional anaesthesia and image-guided interventional pain procedures. BJA Educ. 2024 Jun;24(6):191-202. doi: 10.1016/j.bjae.2024.02.005. Epub 2024 Apr 8. No abstract available.

Study record dates

Study Major Dates

• Study Start (Estimated): June 1, 2025
• Primary Completion (Estimated): February 1, 2026
• Study Completion (Estimated): March 1, 2026

Study Registration Dates

• First Submitted: March 13, 2025
• First Submitted That Met QC Criteria: March 19, 2025
• First Posted (Estimated): March 26, 2025

Study Record Updates

• Last Update Posted (Estimated): March 26, 2025
• Last Update Submitted That Met QC Criteria: March 19, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Keywords: total hip arthroplasty; Hip; Sciatic nerve block; Anatomy; peng block
• Other Study ID Numbers: COS-RGDS-2024-06-039-P-ELMALEH

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No