The Effects of Demographic and Clinical Data of Patients on Cerebral Oxygen Monitoring Values

January 4, 2026 updated by: Tuna Şahin

The Effects of Demographic and Clinical Data of Patients on the Assessment of Cerebral Oxygen Monitoring Values Applied During Coronary Artery Bypass Grafting

The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS). The primary outcome measure of the study is the regional oxygen saturation (rSO2) values measured on the monitor at twelve time points. The other primary outcome measures consist of baseline arterial and venous blood gas analysis and baseline activated clotting time measurements.

Study Overview

Status

Completed

Conditions

Detailed Description

This prospective observational study analyzes 80 patients between the ages of 25-80 years who are undergoing elective coronary artery bypass grafting (CABG) surgery. Demographic data of the patients such as age, gender, comorbidities, body mass index are recorded. In addition to standard monitoring, cerebral oximetry monitoring (NIRS) is applied to the patients. Baseline arterial and venous blood gas analysis values, baseline activated clotting time measurements are recorded. Durations of anesthesia, surgery , cardiopulmonary bypass , aortic cross- clamping are recorded. Time points for rSO2 values are baseline, induction, sternotomy, cannulation, pump entry, cross clamp placement, 34º C ,36º C, lowest temperature, cross clamp removal, pump exit, skin closure.

Study Type

Observational

Enrollment (Actual)

80

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

Patients undergoing elective coronary artery bypass grafting surgery

Description

Inclusion criteria:

  • Accepting to participate in the study
  • Undergoing elective coronary artery bypass grafting surgery
  • Age 25-80 years Ejection fraction 30% and above

Exclusion criteria:

  • Non volunteers
  • Age <25 or >80 years
  • Ejection fraction below 30%
  • Patients with history of neurological disease or neurosurgery
  • Emergency surgery
  • Concurrent valve surgery
  • Patients with history of carotid artery stenosis
  • Patients with need for preoperative intraaortic balloon pump or inotropic support

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Regional oxygen saturation values
Time Frame: Baseline and peroperative measurements until the and of surgery
Regional oxygen saturation values measurement at twelve points.
Baseline and peroperative measurements until the and of surgery
Baseline arterial blood gas analysis
Time Frame: Within 5 minutes after arterial cannulation for the baseline measurement
The baseline arterial blood gas sample taken from the patient after arterial cannulation
Within 5 minutes after arterial cannulation for the baseline measurement
Venous blood gas analysis
Time Frame: Within 5 minutes after central jugular venous cannulation
Venous blood gas sample taken from the patient after central jugular venous cannulation
Within 5 minutes after central jugular venous cannulation
Baseline activated clotting time measurement
Time Frame: Within 5 minutes after arterial cannulation for the baseline measurement
The baseline measurement of activated clotting time after arterial cannulation
Within 5 minutes after arterial cannulation for the baseline measurement

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Tuna Şahin

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 12, 2025

Primary Completion (Actual)

December 31, 2025

Study Completion (Actual)

December 31, 2025

Study Registration Dates

First Submitted

September 30, 2025

First Submitted That Met QC Criteria

November 13, 2025

First Posted (Estimated)

November 14, 2025

Study Record Updates

Last Update Posted (Actual)

January 7, 2026

Last Update Submitted That Met QC Criteria

January 4, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • Adana City TRH

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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