The Effectiveness of Transcranial Magnetic Stimulation and Mirror Therapy in Hemispatial Neglect

February 22, 2026 updated by: Ayse Naz Kalem, Ankara Etlik City Hospital

Evaluation of the Effectiveness of Transcranial Magnetic Stimulation and Mirror Therapy in Hemispatial Neglect Developing After Stroke

The aim of this study is to evaluate the effectiveness of continuous Theta Burst Stimulation added to mirror therapy on neglect associated with stroke.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

22

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: Ayse Naz Kalem Ozgen, Specialist
  • Phone Number: +90 0312 797 00 00
  • Email: kalemnaz@gmail.com

Study Locations

  • Turkey (Türkiye)
    • Yenimahalle
      • Ankara, Yenimahalle, Turkey (Türkiye), 06010
        • Recruiting
        • Ankara Etlik City Hospital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Ischemic/haemorrhagic stroke
  2. Right hemisphere lesion
  3. Patients with a duration of more than 7 days but less than 1 year from the date of the event
  4. Aged between 18 and 75 years
  5. Patients with a Mini Mental Test Score ≥ 24

Exclusion Criteria:

  1. History of recurrent stroke
  2. Presence of vision or hearing problems
  3. Use of medication affecting cognitive function
  4. History of epilepsy
  5. Pregnancy or breastfeeding
  6. History of malignancy
  7. Pacemaker
  8. Presence of metallic implants in the brain or scalp (including cochlear implant)
  9. History of premorbid dementia
  10. Presence of psychiatric or additional neurological disease

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Active cTBS + mirror therapy group
Other: Mirror Therapy
Mirror therapy will be administered 5 days a week for 2 weeks.
Device: cTBS
Patients received cTBS applied to the P3 region according to the 10/20 electroencephalogram system for 5 days a week, totalling 10 sessions over 2 weeks.
Other: Cognitive rehabilitation
Methods that facilitate adaptation in daily life activities will be taught.
Sham Comparator: Sham cTBS + mirror therapy
Other: Mirror Therapy
Mirror therapy will be administered 5 days a week for 2 weeks.
Other: Cognitive rehabilitation
Methods that facilitate adaptation in daily life activities will be taught.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Catherine Bergego Scale
Time Frame: Before Treatment and 2nd week of treatment
Before Treatment and 2nd week of treatment

Secondary Outcome Measures

Outcome Measure
Time Frame
Verbal and Nonverbal Cancellation Test
Time Frame: Before Treatment and 2nd week of treatment
Before Treatment and 2nd week of treatment
Line Bisection Test
Time Frame: Before Treatment and 2nd week of treatment
Before Treatment and 2nd week of treatment
Barthel Index
Time Frame: Before Treatment and 2nd week of treatment
Before Treatment and 2nd week of treatment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara Etlik City Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2026

Primary Completion (Estimated)

January 31, 2027

Study Completion (Estimated)

January 31, 2027

Study Registration Dates

First Submitted

November 13, 2025

First Submitted That Met QC Criteria

November 13, 2025

First Posted (Actual)

November 14, 2025

Study Record Updates

Last Update Posted (Actual)

February 24, 2026

Last Update Submitted That Met QC Criteria

February 22, 2026

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AEŞH-EK-2025-164

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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