Virtual Reality in Sedentary Adults With Hamstring Shortening

April 11, 2026 updated by: Nesma Morgan Allam, Cairo University

Impact of Virtual Reality on Flexibility, Muscle Strength and Gait Parameters in Sedentary Adults With Hamstring Shortening: A Randomized Controlled Trial

Tightness of hamstring muscle is known as a reduction in range of motion accompanied by a sensation of restriction in the posterior aspect of thigh. Numerous reasons can cause it, such as genetic susceptibility, compensatory tightness due to persistent abnormalities, and muscular strain. Tight hamstrings cause a small amount of knee flexion during exercise and require comparatively high quadriceps efforts to offset the hamstrings' passive resistance. This could result in knee joint pain that affects gait and raise the reaction forces at the patellofemoral joint.

Study Overview

Study Type

Interventional

Enrollment (Actual)

84

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Giza, Egypt
        • Faculty of physical therapy, Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Sedentary adults with tightness of hamstring muscle with the degree of flexion for knee joint more than 20° throughout active knee extension (AKE) test.
  • Their age between 18 and 30 years.
  • BMI less than 30 kg/ m2 .
  • Sedentary lifestyle that includes sitting on the chair for long period of time for minimum 6 hours per day, 5 days/week for 6 months minimally.
  • Participants who did not engaged in a physiotherapy programs in the previous 6 months.
  • Absence of fractures, injuries or medications (such as analgesics or muscle relaxants) that may affect the results of the study.

Exclusion Criteria:

  • Any neurological diseases (such as; severe disc prolapse and radiating pain).
  • Injury of hamstring in the previous 2 years.
  • History of knee injury.
  • Fracture in lower extremity or the spine.
  • Surgery in the spine.
  • Unequal leg length > 2cm.
  • Congenital deformity.
  • Orthopedic disorders such as patellofemoral pain syndrome, musculoskeletal pain, psychiatric problem.
  • Any systemic disease, hearing or visual deficits, cognitive, or cardiovascular complications, and pregnancy.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Group A (Virtual reality group)
Participants will receive virtual reality (VR) in addition to the traditional physical therapy program 2 times/week for 5 weeks.
A five-minute warm-up, thirty minutes of intervention training, and a five-minute cool-down will all be included in each session. Five minutes of stretching and walking were part of the warm-up. Every participant will play five sports games (running, cool-running, catching gift, football, skate) during each session. These gamed can help teenagers to improve their physical strength, endurance, balance, and coordination. Every game lasted Five minutes.
The exercise programme includes farmer walks, squats, calf raises, stretching exercises, and strengthening activities. The exercises will be performed in one or two sets of 15-20 repetitions, with a 60-second rest in between. The sets, repetitions, and loads will be increased as the participants advance, up to three sets of 60 repetitions for a perceived effort of 70%-80% of 1RM
Active Comparator: Group B (control group)
Participants will receive a traditional physical therapy program only, 2 times per week for 5 weeks.
The exercise programme includes farmer walks, squats, calf raises, stretching exercises, and strengthening activities. The exercises will be performed in one or two sets of 15-20 repetitions, with a 60-second rest in between. The sets, repetitions, and loads will be increased as the participants advance, up to three sets of 60 repetitions for a perceived effort of 70%-80% of 1RM

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Muscle strength
Time Frame: 5 weeks
Microfit hand-held dynamometer (HHD) will be used for assessment of hamstring muscle strength. Each participant will lie prone on a standard treatment table. In this position, the participant will be instructed to bend their knee to 90° of knee flexion, where the Microfet 2 MMT-Wireless HHD will be placed on the lower leg, and a downward force toward the table will be held for 5s while the participant resists the downward force. The participant will be instructed to use their maximum effort. It will be performed three times, and an average will be recorded.
5 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Active Knee Extension (AKE) Test
Time Frame: 5 weeks
A typical, double-arm, plastic goniometer with an arm length of 31.75 cm will be used to measure the AKE angle. With the stationary arm over the thigh and directed to the greater trochanter, and the moving arm over the leg and directed to the lateral malleolus, the goniometer's axis will be fixed over the lateral epicondyle of the femur. The participant will be asked to fully extend the knee of the dominant leg while relaxing their foot. To measure the AKE angle, which is the degree of knee flexion from the last knee extension, they will maintain this position for five seconds.
5 weeks
Step length
Time Frame: 5 weeks
A GAITRite® electronic walkway system, which includes a walkway with overall measurements of 90 cm × 7 m × 3.2 mm, will be used to assess gait metrics. A 9 m × 4 m laboratory space that is protected from light and noise will be used for the examination of step length. First, participants will be instructed to stand at the start line in an orthostatic position to adopt the start position. Following that, participants will be told to walk along the GAITRite® system's walkway at their own pace, pausing at the goal line.
5 weeks
Cadence
Time Frame: 5 weeks
A GAITRite® electronic walkway system, which includes a walkway with overall measurements of 90 cm × 7 m × 3.2 mm, will be used to assess gait metrics. A 9 m × 4 m laboratory space that is protected from light and noise will be used for the examination of cadence. First, participants will be instructed to stand at the start line in an orthostatic position to adopt the start position. Following that, participants will be told to walk along the GAITRite® system's walkway at their own pace, pausing at the goal line.
5 weeks
Velocity
Time Frame: 5 weeks
A GAITRite® electronic walkway system, which includes a walkway with overall measurements of 90 cm × 7 m × 3.2 mm, will be used to assess gait metrics. A 9 m × 4 m laboratory space that is protected from light and noise will be used for the examination of velocity. First, participants will be instructed to stand at the start line in an orthostatic position to adopt the start position. Following that, participants will be told to walk along the GAITRite® system's walkway at their own pace, pausing at the goal line.
5 weeks
Stride length
Time Frame: 5 weeks
A GAITRite® electronic walkway system, which includes a walkway with overall measurements of 90 cm × 7 m × 3.2 mm, will be used to assess gait metrics. A 9 m × 4 m laboratory space that is protected from light and noise will be used for the examination of velocity. First, participants will be instructed to stand at the start line in an orthostatic position to adopt the start position. Following that, participants will be told to walk along the GAITRite® system's walkway at their own pace, pausing at the goal line.
5 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 20, 2025

Primary Completion (Actual)

March 28, 2026

Study Completion (Actual)

April 10, 2026

Study Registration Dates

First Submitted

November 14, 2025

First Submitted That Met QC Criteria

November 18, 2025

First Posted (Actual)

November 20, 2025

Study Record Updates

Last Update Posted (Actual)

April 15, 2026

Last Update Submitted That Met QC Criteria

April 11, 2026

Last Verified

November 1, 2025

More Information

Terms related to this study

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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