Hypermobility, Foot Posture, and Scoliosis Severity (AIS)

November 28, 2025 updated by: Tuğçe Yavuz, Istinye University

Investigation of the Relationship Between Hypermobility, Foot Posture, and Scoliosis Severity in Adolescents With Idiopathic Scoliosis

Adolescent Idiopathic Scoliosis is a three-dimensional spinal deformity that may also affect joint mobility, lower limb alignment, and overall posture. Joint hypermobility and foot posture abnormalities, including pronation or supination, are commonly observed in adolescents and may contribute to postural imbalance or altered biomechanical loading. However, the relationship between hypermobility, foot posture, and the severity of scoliosis remains unclear.

The aim of this study is to examine whether generalized joint hypermobility and foot posture characteristics are associated with Cobb angle severity in adolescents diagnosed with Adolescent Idiopathic Scoliosis. Hypermobility will be assessed using the Beighton Score, and foot posture will be evaluated with the Foot Posture Index. Understanding these associations may help clinicians better evaluate biomechanical factors related to scoliosis and guide future preventive or therapeutic approaches.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

40

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

The study population consists of adolescents aged 10 to 19 years who have been clinically and radiographically diagnosed with Adolescent Idiopathic Scoliosis. Participants must have a Cobb angle of at least 10° and be able to complete physical assessments, including hypermobility and foot posture evaluations.

Description

Inclusion Criteria:

  • Diagnosis of Adolescent Idiopathic Scoliosis
  • Age 10-19 years
  • Cobb angle ≥ 10° on standing Anterior-Posterior radiograph
  • Ability to participate in physical assessments
  • Voluntary consent to participate

Exclusion Criteria:

  • Neuromuscular, syndromic, or congenital scoliosis
  • Previous spinal surgery
  • Lower extremity orthopedic conditions affecting foot posture
  • Neurological or rheumatological disorders affecting joint mobility
  • Communication or cognitive difficulties limiting participate

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Adolescent Idiopathic Scoliosis Group
Participants diagnosed with Adolescent Idiopathic Scoliosis will undergo assessments of hypermobility (Beighton Score), foot posture (Foot Posture Index), and scoliosis severity (Cobb angle).
Other: Assessment
Participants diagnosed with Adolescent Idiopathic Scoliosis will undergo assessments of hypermobility (Beighton Score), foot posture (Foot Posture Index), and scoliosis severity (Cobb angle).

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The Beighton Test
Time Frame: 4 weeks
This is a standardized and easily applicable clinical assessment method used to determine joint hypermobility. The total score for the nine-item test ranges from 0 to 9. A total score of ≥4 indicates the presence of hypermobility. It is scored out of 9 points; each positive finding is evaluated as 1 point.
4 weeks
Foot Posture Index-6
Time Frame: 4 weeks
The Foot Posture Index-6 is a reliable and valid clinical assessment tool used to objectively evaluate foot posture in the pronation-supination spectrum. The assessment is performed with the individual in a relaxed standing position and is based on six observational criteria. The total score ranges from -12 to +12, where higher scores indicate a more pronated foot posture, while lower scores reflect a more supinated posture. A score close to 0 represents a neutral foot posture.
4 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Feiss Line Test
Time Frame: 4 weeks
Used to evaluate the structural characteristics of the arch of the foot. In this test, the position of the navicular tubercle above or below a line drawn by aligning the medial malleolus, navicular tubercle, and first metatarsal head indicates the presence of pes planus or pes cavus.
4 weeks
Sit-Reach Test
Time Frame: 4 weeks
This is a common field test that evaluates the flexibility of the hamstring and lumbar muscles. The participant sits in a straight position, knees straight, and the soles of their feet touching the test box, reaching forward; the distance between their toes indicates the level of flexibility.
4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istinye University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

December 15, 2025

Primary Completion (Estimated)

March 15, 2026

Study Completion (Estimated)

March 30, 2026

Study Registration Dates

First Submitted

November 18, 2025

First Submitted That Met QC Criteria

November 18, 2025

First Posted (Estimated)

November 25, 2025

Study Record Updates

Last Update Posted (Actual)

December 5, 2025

Last Update Submitted That Met QC Criteria

November 28, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 25-121

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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