Periodontal Status and Disease Severity in Hidradenitis Suppurativa Patients

December 20, 2025 updated by: Şeyma Çardakçı, Saglik Bilimleri Universitesi

Evaluation of Periodontal Status in Individuals With Hidradenitis Suppurativa: A Cross-Sectional Study

This cross-sectional study aims to evaluate the periodontal status of individuals diagnosed with hidradenitis suppurativa (HS) and to compare them with systemically healthy controls. HS is a chronic inflammatory skin disease characterized by recurrent lesions and systemic inflammation, which may influence periodontal health. In this study, periodontal parameters-including probing depth, clinical attachment loss, gingival index, plaque index, and bleeding on probing-will be assessed using standard clinical methods. Dermatological examination will include disease duration, lesion characteristics, and Hurley staging. The study will investigate the prevalence of periodontitis in HS patients and explore potential associations between periodontal findings and HS severity. Findings from this research may provide insight into shared inflammatory pathways and contribute to understanding the possible link between HS and periodontal disease.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

226

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • None Selected
      • Ankara, None Selected, Turkey (Türkiye), 6220
        • University of Health Sciences, Gülhane Faculty of Dentistry

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

The study population consists of adult individuals with a confirmed diagnosis of hidradenitis suppurativa and age-matched healthy controls, each having at least 12 teeth (excluding third molars), and no recent periodontal or systemic treatment.

Description

Inclusion Criteria:

  • Having a diagnosis of hidradenitis suppurativa.
  • Age greater than 18 years.
  • Presence of at least 12 teeth in the mouth, excluding third molars.

Exclusion Criteria:

  • Age under 18 years.
  • Pregnancy.
  • Breastfeeding.
  • Receiving treatment for periodontitis or hidradenitis suppurativa within the past 3 months.
  • Use of antibiotics, anti-inflammatory drugs, or immunomodulatory medications within the past 3 months.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Hidradenitis Suppurativa Group
Participants diagnosed with hidradenitis suppurativa undergoing periodontal examination.
Other: No intervention (observational study)
Observational study with no treatment or intervention applied.
Healthy Control Group
Systemically healthy individuals without hidradenitis suppurativa undergoing periodontal examination.
Other: No intervention (observational study)
Observational study with no treatment or intervention applied.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Correlation Between Periodontal Status and Hidradenitis suppurativa
Time Frame: Baseline (single assessment)
Baseline (single assessment)

Secondary Outcome Measures

Outcome Measure
Time Frame
Correlation between Periodontal Status and Hurley Stage
Time Frame: Baeline (single assesment)
Baeline (single assesment)
Corralation between Hurley Stage and Oral Health Impact Profile OHIP-14) Score
Time Frame: baseline (single assesment)
baseline (single assesment)
Correlation between Dermatology Life Quality Index (DLQI) and Oral Health Impact Profile (OHIP-14) Total Score
Time Frame: baseline (single assesment)
baseline (single assesment)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saglik Bilimleri Universitesi

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 1, 2025

Primary Completion (Actual)

September 1, 2025

Study Completion (Actual)

September 15, 2025

Study Registration Dates

First Submitted

December 8, 2025

First Submitted That Met QC Criteria

December 8, 2025

First Posted (Estimated)

December 19, 2025

Study Record Updates

Last Update Posted (Actual)

December 29, 2025

Last Update Submitted That Met QC Criteria

December 20, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • SUDE1824

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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