VR-Live Hybrid Neurosurgery Clerkship:Boosting Neurosurgical Presence & Decisions

December 11, 2025 updated by: Zhigang Lan, West China Hospital

Enhancing Clinical Presence and Decision-Making in Neurosurgical Clerkships: A Hybrid Model Integrating Virtual Reality and Live-Streamed Encounters

The goal of this randomized controlled trial was to learn whether a hybrid telemedicine curriculum that combines virtual-reality (VR) simulation with interactive live-streamed neurosurgical cases improves neurosurgical intentionality and clinical decision-making in fourth-year medical students whose clerkships were disrupted by COVID-19. It also assessed technical skills, theoretical knowledge, and student experience. The main questions it aimed to answer were:

Does the 4-week hybrid model (VR + live cases) produce greater gains in neurosurgical intentionality and decision-making than traditional online videos and readings? Does the hybrid model improve VR technical skill performance and student satisfaction without harming theoretical knowledge? Researchers randomized 112 students 1:1 to the hybrid intervention (15 h VR neuroanatomy/procedures + 20 h live-streamed surgeries/ICU rounds + real-time Q&A) or a time-matched control group (pre-recorded videos, textbook readings, asynchronous forums).

Participants in both groups:

Completed 40 hours of remote content over 4 weeks Were tested at baseline and post-course on intentionality (modified Zwisch scale), decision-making (neurosurgery-specific SCT), 50-item MCQ knowledge, and VR proficiency metrics Joined focus groups and rated satisfaction on a 5-point Likert scale

Study Overview

Study Type

Interventional

Enrollment (Actual)

112

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Sichuan
      • Chengdu, Sichuan, China
        • West China Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Fourth-year medical students assigned to the neurosurgical clerkship rotation
  2. Able to participate fully in remote learning (stable internet and VR-headset compatible computer)
  3. Provided written informed consent

Exclusion Criteria:

  1. Had already completed a prior neurosurgical elective
  2. Lacked reliable internet access or hardware required for VR/live-streaming
  3. Declined to consent or unable to complete the 4-week curriculum

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Intervention Group
  1. VR Simulation (15 hours): Customized modules on the NeuroVR Platform (validated for neurosurgical education):

    • Neuroanatomy (5 hours): 3D interactive models of cerebral cortex, brainstem, cranial nerves, and spinal cord (with vascular/meningeal overlays).
    • Procedural skills (10 hours): Craniotomy basics, ventriculostomy, lumbar puncture, and spine decompression-with real-time feedback on instrument handling and anatomical precision.
  2. Live-Streamed Neurosurgical Procedures (20 hours): 18 diverse cases (brain tumor resection [n=6], spine fusion [n=5], aneurysm clipping [n=3], epilepsy surgery [n=4]) via HIPAA-compliant Zoom for Healthcare. Each session included:

    • Pre-procedure briefing (anatomical landmarks, surgical goals).
    • Intraoperative expert commentary (neurosurgeon + neuroanesthesiologist).
    • Real-time Q&A (focused on neurocritical decision-making: e.g., "How do you adjust resection for eloquent cortex mapping?").
  3. Live-Streamed Neurocritical Care Rounds (5 hours): Week
No Intervention: Control group
  • Pre-recorded neurosurgical videos (20 hours): Matched case types from the Neurosurgical Education and Training Resource (NETR) library, with voiceover but no interactivity.
  • Textbook/journal readings (15 hours): Chapters from Neurosurgery: The Essential Guide and articles from Journal of Neurosurgical Education (aligned with case content).
  • Asynchronous case discussions (5 hours): Text-based forums on the institution's LMS, moderated by faculty (48-hour response window).

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Neurosurgical Intentionality
Time Frame: 4 weeks
Neurosurgical Intentionality: Intervention group post-intervention scores were compared with controls, the higer the score, the better the outcome
4 weeks
Clinical decision-making score
Time Frame: 4 weeks

Clinical Decision-Making Score Range: 24-120 points (5-point Likert, 24 items)

Levels:

24-48 = low 49-84 = moderate 85-120 = high The higher the score, the better the outcome

4 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Theoretical Knowledge
Time Frame: 4 weeks
These comprised of theoretical knowledge with 50-item multiple-choice-questions (MCQ) exam on neuroanatomy, pathology, and surgical indications ,the higer the score, the better the outcome
4 weeks
Technical Skill Performance score
Time Frame: 4 weeks
Technical Skill Performance with VR proficiency metrics such as time to completion, anatomical accuracy, and instrument error rate from NeuroVR's built-in assessment tool. The higer the score,the better the outcome
4 weeks
Student experience score
Time Frame: 4 weeks
Student experience using semi-structured focus groups such as 6 groups of 8-10 students/group and reflective journals, analyzed via Braun & Clarke's thematic analysis ; and satisfaction using 12-item Likert scale (1=strongly dissatisfied to 5=strongly satisfied) measuring curriculum relevance, engagement, and skill development. The higher the score, the better the outcome
4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2023

Primary Completion (Actual)

April 30, 2024

Study Completion (Actual)

December 1, 2024

Study Registration Dates

First Submitted

December 2, 2025

First Submitted That Met QC Criteria

December 11, 2025

First Posted (Actual)

December 26, 2025

Study Record Updates

Last Update Posted (Actual)

December 26, 2025

Last Update Submitted That Met QC Criteria

December 11, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • WestChinaH-HX-2025-03

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Protocol

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • ICF

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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