The Aim of the Study is to Examine the Variation in Blood Pressure Between an Optimal Measurement (According to Established Guidelines in the Literature - Per Guidelines) and a 'Common' Measurement (Used by Nursing Teams - Per Common Practice) Among Women of Reproductive Age With and Without Hyperte

Standard vs. Routine Blood Pressure Measurement in Pregnancy: Effects of Position and Diurnal Variation

The aim of the study is to examine the variation in blood pressure between an optimal measurement (according to established guidelines in the literature - per guidelines) and a 'common' measurement (used by nursing teams - per common practice) among women of reproductive age with and without hyperte

Study Overview

• Status: Recruiting
• Conditions: Blood Pressure Measurement in Pregnancy
• Intervention / Treatment: Procedure: blood pressure measurement

Detailed Description

Accurate blood pressure measurement is a cornerstone of the diagnosis and management of hypertension. The latest Clinical Practice Guidelines (AHA2020- International Society of Hypertension Global) emphasize several important steps for accurate blood pressure measurement, including choosing the correct cuff size, resting for five minutes, sitting with support for the back, feet flat on the floor, and legs uncrossed, and proper arm positioning (i.e., positioning the midpoint of the cuff at heart level with the arm supported on a table or work surface). Sitting measurements are preferred because of the large amount of data linking blood pressure measurements in this position to health outcomes.

• Study Type: Interventional
• Enrollment (Estimated): 500
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Ikhlas IM Ammash, M.D; Phone Number: +972-4-7744602; Email: AnnaTu@hymc.gov.il

Study Locations

• Israel
  • Israel
    • Hadera, Israel, Israel, 3881000
      • Recruiting
      • Hille Yaffe Medical Center
      • Contact: Anna Turetzky, S.N; Phone Number: +972-4-7744602; Email: AnnaTu@hymc.go

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Women aged 18-40
• Informed consent to participate.

Exclusion Criteria:

• Inability to cooperate with BP measurement under optimal conditions
• Women with complex underlying disease that may bias the data (e.g. significant vasculopathy)

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Screening
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: variation in blood pressure between an optimal measurement and a 'common' measurement	Procedure: blood pressure measurement; examine the variation in blood pressure between an optimal measurement (according to established guidelines in the literature - per guidelines) and a 'common' measurement (used by nursing teams - per common practice) among women of reproductive age with and without hypertention

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean difference in systolic blood pressure (mmHg) between guideline-based and routine clinical measurement	Mean difference in systolic blood pressure (mmHg) between guideline-based and routine clinical measurement Description: Systolic blood pressure (SBP) will be measured in each participant using two methods: guideline-based blood pressure measurement performed according to international hypertension guidelines (seated position, appropriate cuff size, arm supported at heart level after ≥5 minutes of rest), and; routine clinical blood pressure measurement as performed by nursing staff under usual clinical conditions. The primary outcome will be the within-participant mean difference in SBP (mmHg) between the two measurement methods.	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean difference in diastolic blood pressure (mmHg) between guideline-based and routine clinical measurement	As above, for diastolic blood pressure (DBP).	1 year
Mean difference in mean arterial pressure (mmHg) between guideline-based and routine clinical measurement	Mean arterial pressure (MAP) will be calculated as MAP = (SBP + 2×DBP) / 3 for each measurement method. The outcome will be the within-participant difference between methods	1 yaer

Collaborators and Investigators

• Sponsor: Hillel Yaffe Medical Center

Study record dates

Study Major Dates

• Study Start (Actual): August 24, 2025
• Primary Completion (Estimated): August 24, 2026
• Study Completion (Estimated): August 24, 2026

Study Registration Dates

• First Submitted: November 16, 2025
• First Submitted That Met QC Criteria: December 21, 2025
• First Posted (Actual): January 6, 2026

Study Record Updates

• Last Update Posted (Actual): January 6, 2026
• Last Update Submitted That Met QC Criteria: December 21, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: 0111-25

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No