- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07351097
Adding Mini-squat Exercises to Leg Press Exercise on Quadriceps and Hamstring Strength and H:Q Ratio in Athletes
March 25, 2026 updated by: Nasr Awad Abdelkader Othman, Cairo University
Effect of Adding Mini-squat Exercises at Different Angles to Leg Press Exercise on Quadriceps and Hamstring Strength and H:Q Ratio in Athletes
This study will try to answer the following question:
Will adding mini-squat exercises at different angles (30°,45°, and 60°) to leg press exercise influence quadriceps and hamstring strength and H:Q angle in football players?
Study Overview
Status
Completed
Conditions
Detailed Description
Recent studies have highlighted the importance of exercise selection and angle specificity in resistance training, showing that different knee angles result in varied activation patterns in the quadriceps and hamstrings.
However, current literature offers limited insight into the effects of integrating mini squat exercises with leg press training on injury prevention and functional outcomes in athletic populations.
In particular, there is a lack of literature on how such a combined leg press and mini squat exercise at different angles influences the H:Q ratio, lower limb neuromuscular control, and performance in young male football players.
Therefore, the present study aims to examine whether incorporating mini squats performed at varying knee flexion angles into a leg press training program can improve muscle balance and lower limb strength in football players.
The findings may provide valuable guidance for physiotherapists, coaches, and sports scientists in developing evidence-based, angle-specific exercise protocols tailored to the functional demands of athletes.
Study Type
Interventional
Enrollment (Actual)
60
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Jizan, Saudi Arabia
- Jazan University Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Male football players aged between 18-30 years (Scoz et al., 2021).
- Body Mass Index (BMI) between 18.5 and 24.9 kg/m² (Walsh et al., 2018 & Sattar& Lean, 2009).
- Currently training or playing with a registered football club/team.
- Hamstring-to-Quadriceps (HQ) strength ratio of ≥ 0.6 (Çelebi et al., 2018).
- Having no oral or injectable non-steroidal anti-inflammatory drugs (NSAID), 2weeks before starting study.
- Having no oral injectable corticosteroids 3 months before starting the study.
Exclusion Criteria:
- History of acute or chronic injury to the knee, hip, or ankle joint
- Undergoing any other rehabilitation or physical therapy programs during the six weeks before starting the study
- Diagnosed with neurological or systemic disorders affecting muscle function or balance
- Participation in competitive sports or high-intensity training outside the study protocol during the study period
- Presence of any contraindication to exercise, such as uncontrolled hypertension or heart conditions.
- Clinically free from lower limb injuries.
- Having no history of neurological, cardiovascular, or musculoskeletal disorders.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Group A (mini-squat at 30° knee flexion and leg press)
Fifteen participants will receive mini-squat exercises at 30° knee flexion and leg press exercises
|
mini-squat exercises at 30° knee flexion and leg press exercises
|
|
Active Comparator: Group B (mini-squat at 45° knee flexion and leg press)
Fifteen participants will receive mini-squat exercises at 45° knee flexion and leg press exercises
|
mini-squat exercises at 45° knee flexion and leg press exercises
|
|
Active Comparator: Group C (mini-squat at 60° knee flexion and leg press)
Fifteen participants will receive mini-squat exercises at 60°and leg press exercises
|
mini-squat exercises at 60°and leg press exercises
|
|
Placebo Comparator: Group D (Control group: leg press exercise program only)
Fifteen participants will receive leg press exercise program only.
|
leg press exercise program only
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Measurement of quadriceps strength
Time Frame: 1.5 months
|
|
1.5 months
|
|
Measurement of hamstrings muscle strength
Time Frame: 1.5 months
|
All previously described quadriceps muscle evaluation procedures will be applied for the hamstrings muscle strength test; however, the range of motion will be set from full knee extension, and the participant will be instructed to actively bend the knee against the resistance of the device to 90°
|
1.5 months
|
|
Hamstring to quadriceps H:Q ratio calculation
Time Frame: 1.5 months
|
The H-Q ratio refers to the relative strength of the hamstring muscles compared to the quadriceps, typically measured under isokinetic conditions (at the same angular velocity).
It is calculated as the maximal concentric knee flexion strength divided by maximal concentric knee extension strength.
|
1.5 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Prof.Dr.Nasr Abdelkader, Cairo Univesity
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
September 2, 2025
Primary Completion (Actual)
March 3, 2026
Study Completion (Actual)
March 3, 2026
Study Registration Dates
First Submitted
December 31, 2025
First Submitted That Met QC Criteria
January 10, 2026
First Posted (Actual)
January 20, 2026
Study Record Updates
Last Update Posted (Actual)
March 27, 2026
Last Update Submitted That Met QC Criteria
March 25, 2026
Last Verified
January 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- P.T.REC/012/006017
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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