Modex, a Cloud-based, Centralized Health Economic Model Marketplace to Reduce Costs and Enhance Equity in Cancer

January 21, 2026 updated by: Renee JG Arnold, PharmD, Arnold Consultancy & Technology, LLC
The investigators intend to create and test an interactive prototype of an online health economic model platform, ModEx™ (renamed HModEx®), to house oncology models. The primary objective is to create the HModEx® health economic model platform. The secondary objective is to conduct usability testing of search, quality and collaboration on the HModEx® prototype for 20 oncology health economic models with expert advisory panel participants.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Primary Endpoint: Iteratively unit test 4 tasks (A) Revise model platform and back end, (B) Refine the model taxonomy/characterization (i.e., ontology) and search module, (C) Revamp submission module, and (D) Implement paid modules) individually to ascertain 100% pass of common functionality (e.g., searching, uploading, and evaluating models) in the system back end and then iteratively perform integration testing via the front-end user interface until 100% pass using the System Usability Scale (as below). The System Usability Scale yields a single number representing a composite measure of the overall usability of the system being studied. To calculate the System Usability Scale score, first sum the score contributions from each item. Each item's score contribution will range from 0 to 4. For items 1,3,5,7, and 9 the score contribution is the scale position minus 1. For items 2,4,6,8 and 10, the contribution is 5 minus the scale position. Multiply the sum of the scores by 2.5 to obtain the overall value of System Usability Score; scores range from 0 to 100, with higher numbers being better.

Secondary Endpoints: Measure the success of Aim 2 by (1) completion of 80% of tasks in usability testing with scores of ≥68 on the System Usability Scale, a validated questionnaire, and (2) satisfaction with the site. Testing will focus on user interaction with the system, emphasizing effectiveness, efficiency, engagingness, error tolerance, and ease of learning. Specifically, the investigators will assess the ability of the project team and Advisory Panel member participants to log into the platform, configure and manage their modeling projects, and annotate or categorize them in accordance with an ontological index. The investigators will assign participants to interact with at least 2 randomly selected models and associated data files, iterating on this milestone until the investigators achieve 100% success.

Study Type

Interventional

Enrollment (Actual)

9

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Florida
      • Miami Beach, Florida, United States, 33139
        • Arnold Consultancy & Technology, LLC

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Expert Advisory Panel member

Exclusion Criteria:

  • Non-English-speaker

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Advisory Panelist participa will evaluate wireframes and a working prototype of the HModEx® website.
This is a single-arm study that will build and evaluate (via usability testing) an open source health economic model platform prototype using a 9-member expert advisory panel of health economist participants from the US and Europe.
Other: open source health economic models
open source health economic models

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Alpha testing of wireframe usability
Time Frame: 2 months
Iteratively unit test 4 tasks (A) Revise model platform and back end, (B) Refine the model taxonomy/characterization (i.e., ontology) and search module, (C) Revamp submission module, and (D) Implement paid modules) individually to ascertain 100% pass of common functionality (e.g., searching, uploading, and evaluating models) in the system back end and then iteratively perform integration testing via the front-end user interface until 100% pass using the System Usability Scale. The overall value of the System Usability Score ranges from 0 to 100. The higher the score on the System Usability Scale, the better.
2 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Beta testing of prototype usability
Time Frame: 4 months
Measure the success of Aim 2 by (1) completion of 80% of tasks in usability testing with scores of ≥68 on the System Usability Scale, a validated questionnaire, and (2) satisfaction with the site. Testing will focus on user interaction with the system, emphasizing effectiveness, efficiency, engagingness, error tolerance, and ease of learning. Specifically, the investigators will assess the ability of the project team and Advisory Panel member participants to log into the platform, configure and manage their modeling projects, and annotate or categorize them in accordance with an ontological index. The investigators will assign panelist participants to interact with at least 2 randomly selected models and associated data files, iterating on this milestone until the investigators achieve 100% success. The overall value of the System Usability Score ranges from 0 to 100. The higher the score on the System Usability Scale, the better.
4 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Arnold Consultancy & Technology, LLC

Collaborators

National Cancer Institute (NCI)

Investigators

  • Principal Investigator: Renee JG Arnold, PharmD, Arnold Consultancy & Technology, LLC

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2024

Primary Completion (Actual)

November 20, 2025

Study Completion (Actual)

November 20, 2025

Study Registration Dates

First Submitted

December 6, 2025

First Submitted That Met QC Criteria

January 21, 2026

First Posted (Actual)

January 23, 2026

Study Record Updates

Last Update Posted (Actual)

January 23, 2026

Last Update Submitted That Met QC Criteria

January 21, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1R43CA297808-01 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Actually, this will be aggregated System Usability Score data that will be shared with other researchers and the backgrounds, but not the individual identities, of the participants will be disclosed in presentations and publications.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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