- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05762562
Parkinson Disease Telerehabilitation Program (PDTR): a Home-motor Program. A Pilot Study.
Parkinson Disease Telerehabilitation Program (PDTR): a Home-motor Program for Parkinson's Disease With Open-source Platforms. A Pilot Study.
Parkinson's disease (PD) leads to multifactorial disabilities with consequent social restrictions, especially in the COVID-19 era. Continuity of care, especially rehabilitation measures, is critical to improve or maintain an adequate QoL for patients. The Parkinson Disease Telerehabilitation Program (PDTR) is an individualized home rehabilitation program using open-source platforms (OSp).
The main purpose of this pilot study is to investigate the feasibility of TR in patients with PD by using free OS platforms (PDTR PROGRAM).
The target of this study was to have at least 90% of participants completing the program. To complete the program every single patient had to complete at least 80% of the prescribed TR sessions.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Participants were PD patient afferent to the Neurology ambulatory. Patients underwent an initial evaluation (T0) by the neurologist and physiotherapist. During T0, also the level of digital literacy was evaluated
Participants included in the study were separated into three groups based on their residual motor skills evaluated by the Short Physical Performance Battery (SPPB).
Each group corresponded to a Program (Pr). SPPB score between 12 and 10: Pr. A for patients with capable motor skills; they were were associated to the TR program A (TrP.A).
SPPB score between 9 and 7: Pr. B for patients with reduced motor skills; they were were associated to the TR program B (TrP.B).
SPPB score lower than 7: Pr. C for patients who didn't show having sufficient motor skills; they were were associated to the telemonitoring program C (TmP.C) without any exercise program.
Patients who were included in TrP.A and TrP.B underwent a TR program using OS platforms for 8 consecutive weeks.
OS platforms used are: Zoom, Skype, Google Teams, WhatsApp. The patient was given the opportunity to choose the operating system to use based on their knowledge, computer skills and ease of use to facilitate the management of the session.
Patients in TrP.A and TrP.B had to perform at home a tailored exercise program 4 times/week for 45-60 minutes.
Twice a week, the activity was performed with physiotherapist through OSp. A specific exercise program for the parkinsonian patients was structured in relation to the individual residual motor skills based on the FITT - frequency/intensity/type/time - protocol. Both programs, A and B, include multiple exercise: aerobic activities, mobility and stretching exercises for upper and lower limbs, global muscle strengthening, balance & motor coordination training, start and stop exercises and walking training.
The exercises in program A were more complex and showed a higher intensity, while those in program B were simpler, safer and at lower intensity.
Subjects included in TmP.C participated in an 8-weeks program. A video-call was scheduled once a week to monitor the patient's clinical condition without any exercise program.
The target of this study was to have at least 90% of participants completing the program. To complete the program every single patient had to complete at least 80% of the prescribed TR sessions.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
PV
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Pavia, PV, Italy, 27100
- ICS Maugeri
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Hoehn & Yahr (H&Y) score between 1 and 3;
- being on drug treatment stabilized with L-Dopa or dopamine agonists;
- being able to walk independently (with or without help)
- having adequate computer knowledge, be able to use online communication platforms and to undertake a continuous 8-weeks program.
Exclusion Criteria:
- Montreal Cognitive Assessment screening test score below 17.54
- having unpredictable motor fluctuations or non-pharmacologically controlled dyskinesias
- having neurological pathologies superimposed on PD; or cognitive, sensory, psychiatric alterations such as to make it impossible to understand and execute the exercises; or musculoskeletal and cardiopulmonary diseases that compromise mild physical activity.
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Telerehabilitation with OS platforms
Patients with Parkinson's Disease were divided into three subgruops based on their residual motor skills.
|
Telerehabilitation with opensource platforms. Patients enrolled were dived into three groups based on their score in SPPB. Each group corresponded to a Program (Pr): • Pr. A is for patients with capable motor skills, Pr. B is for patients with reduced motor skills, • Pr. C is for patients who didn't show having sufficient motor skills to support a TR program. Patients who were included in TrP.A and TrP.B underwent a TR program using OS platforms for 8 consecutive weeks. A specific exercise program for the parkinsonian patients was structured in relation to the individual residual motor skills based on the FITT - frequency/intensity/type/time - protocol. Twice a week, the activity was performed with the support of a physiotherapist through OS TR platform. Subjects included in TmP.C participated in an 8-weeks program. A video-call was scheduled once a week to monitor the patient's clinical condition without any exercise program. |
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The opportunity of the usage TR in PD patients by using free open-source platforms
Time Frame: 1 year
|
90% of participants completing the program.
To complete the program every single patient had to complete at least 80% of the prescribed TR sessions
|
1 year
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Patient's satisfaction
Time Frame: 1 year
|
Administration of a specific questionnaire to evaluate the patient's satisfaction with TR treatment program with free open-source platforms
|
1 year
|
Patient's agreement
Time Frame: 1 year
|
Administration of a specific questionnaire to evaluate the patient's agreement with TR treatment program with free open-source systems
|
1 year
|
Maintenance of clinical outcomes - Walking speed
Time Frame: 1 year
|
Walking speed using 10 Meter Walking Test (10 MWT) rated in seconds.
Comparison between T0 and T1 in the groups A and B. A descriptive analysis of the results was then conducted.
|
1 year
|
Maintenance of clinical outcomes - Balance
Time Frame: 1 year
|
Balance using MiniBEST Test (values: 0 minimum - 28 maximum).
Comparison between T0 and T1 in the groups A and B. A descriptive analysis of the results was then conducted.
|
1 year
|
Maintenance of clinical outcomes - Risk of falling
Time Frame: 1 year
|
Risk of falling using the Time Up and Go (TUG Test) rated in seconds.
Comparison between T0 and T1 in the groups A and B. A descriptive analysis of the results was then conducted.
|
1 year
|
Perceived level of quality of life
Time Frame: 1 years
|
Evaluation of the level of perceived quality of life using the the Parkinson's Disease Questionnaire (short version)(PDQ-8), (values: 0 minimum - 32 maximum.
The summed scor is then divided by total possible score an given as a percentage score out of 100).
Comparison between T0 and T1 in the groups A and B.
|
1 years
|
Collaborators and Investigators
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- prot. 2486 CE, 06/10/2020
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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