Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea

April 15, 2026 updated by: Narongkorn Saiphoklang, MD, Thammasat University

The goal of this observational study is to compare predictive equations for continuous positive airway pressure (CPAP) with in-laboratory manual titration in patients with obstructive sleep apnea (OSA).

The main question the study aims to answer is:

Which CPAP predictive equation best predicts the optimal CPAP pressure in OSA patients in Thailand? Participants will undergo an in-laboratory sleep study.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

This study is a cross-sectional study involving Thai patients aged 18 years or older with suspected obstructive sleep apnea (OSA). Participants will undergo an in-laboratory sleep study. During the study, sleep technicians will use CPAP predictive equations to estimate the optimal CPAP pressure.

Study Type

Observational

Enrollment (Estimated)

150

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Thailand
      • Pathum Thani, Thailand, 12120
        • Recruiting
        • Faculty of Medicine, Thammasat University
        • Contact:
        • Contact:
      • Pathum Thani, Thailand, 12120
        • Recruiting
        • Narongkorn Saiphoklang
        • Contact:
        • Principal Investigator:
          • Narongkorn Saiphoklang, MD
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients aged 18 years or older with suspected OSA

Description

Inclusion Criteria:

  • Suspected OSA
  • Undergoing an in-laboratory sleep study

Exclusion Criteria:

  • No indication for in-laboratory manual CPAP titration
  • Failure to determine an optimal CPAP pressure during in-laboratory manual CPAP titration

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Obstructive sleep apnea (OSA)
Patients aged 18 years or older with OSA
Diagnostic test: Sleep test
Type 1 polysomnography will be performed in the Sleep Center of Thammasat (SCENT).
Other: Predictive equations of continuous positive airway pressure (CPAP)
CPAP predictive equations will be selected based on evidence from reliable studies.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Accuracy of CPAP equations in predicting the optimal pressure in OSA patients
Time Frame: At baseline
Sensitivity and specificity (%) of CPAP equations in predicting the optimal pressure in OSA patients
At baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Thammasat University

Investigators

  • Principal Investigator: Narongkorn Saiphoklang, Thammasat University Faculty of Medicine

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 1, 2026

Primary Completion (Estimated)

October 31, 2026

Study Completion (Estimated)

December 31, 2026

Study Registration Dates

First Submitted

January 17, 2026

First Submitted That Met QC Criteria

January 22, 2026

First Posted (Actual)

January 29, 2026

Study Record Updates

Last Update Posted (Actual)

April 17, 2026

Last Update Submitted That Met QC Criteria

April 15, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • TUH-EC-OO-0-031/68

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

IPD and documents will be available for sharing immediately after publication for a period of 2 years.

IPD Sharing Time Frame

IPD and documents will be available for sharing immediately after publication for a period of 2 years.

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • SAP

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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