Efficiency of Self Extracted Tooth Graft in Extraction Socket : A Clinical and Radiographic Study

February 1, 2026 updated by: Lim Poh Ling, Mahsa University

Evaluating the Efficacy of Autogenous Tooth Graft (ATG) Material in Socket Preservation: A Clinical and Radiographic Study.

This is the clinical trial. The goal of this clinical trial is to test whether self extracted tooth graft (autogenous tooth graft ) able to preserved the extraction socket effectively. Our aim is to answer is there any difference in dimensional changes in extraction socket in clinically and radiographically Researchers will compare autogenous tooth graft with self-healing extraction socket in radiographic and clinical measurement.

Participant will be randomly allocated into 2 groups ( Test or controlled group) Test group will be autogenous tooth grafting post extraction. After removed any caries, calculus and any gilling material, the extracted tooth will be grind with grinder and processed using BONMAKER machine. (which the bone graft is washed with hydrogen peroxide, hydrogen chloride and alcohol isopropyl) and controlled group will be self healing group. Both group will withdraw 20cc blood for PRF ( Plasma rich fibrin) membrane and place into the socket and secured with suture. They will be reviewed post extraction 1 week ( to ensure there is no infection ) , 2 week ( for suture removal ) , 1 months ( For clinical measurement) , 3 months (For clinical and radiographic measurement) and 6 months (For radiographic measurement).

Study Overview

Status

Enrolling by invitation

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Malaysia
    • Selangor
      • Jenjarum, Selangor, Malaysia, 42610
        • Faculty of Dentistrty

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  1. Age> or equal to 18 years old
  2. Presence of adjacent teeth to the extraction site
  3. Healthy ,or well controlled systemic disease
  4. Lower and upper incisors, lower premolar/ first molar
  5. Full mouth plaque score < 15%
  6. Adequate space for a dental implant restoration *Patient with previous diagnosis of periodontitis will be required to have a successfully completed course of periodontal treatment before enrolment.

Exclusion Criteria:

  1. Smokers and vapers
  2. Acute infection or sinus tract in relation to the tooth that require extraction
  3. Pregnant or lactating women
  4. Patient received antibiotic for past 1 month
  5. Loss of more than 50% buccal or lingual /palatal bone at the time of extraction
  6. Patient on medication that altered bone metabolism or bone healing such as bisphosphonates, chemotherapeutic drugs or immunosuppressive agents

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
No Intervention: Self Healing Group
Self healing in extraction socket
Experimental: Autogenous tooth graft
Autogenous tooth grafting in extraction socket
Procedure: autogenous tooth graft
Extracted tooth will be grind and processed into bone graft . This bone graft material will grafted into the extraction socket

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Socket dimensional changes in autogenous tooth graft group and self healing group
Time Frame: 6 months

Socket dimensional changes will be measure in clinical and radiographic measure Clinical measure: A stent will be made prior extraction and hole on the stent will be made to standardized measurement. Clinical measurement ( socket height) will be measure during post extraction, 1 month, 3 month and 6 month to observe the value of the resorption of the extraction socket . The discrepancy value is will be from ( 1month -baseline, 3month-baseline, 6month- baseline)

Radiographic measure: CBCT will be taken post extraction 3 month and 6month. Socket width will be measure in 3mm below the socket and 5 mm below the socket. Other than that, mimic software will be used for the volumetric changes.
6 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Volumetric changes in autogenous tooth group and self healing group
Time Frame: 6 months
In this , mimic software will be used for volumetric changes
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mahsa University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 1, 2025

Primary Completion (Estimated)

July 30, 2026

Study Completion (Estimated)

December 31, 2026

Study Registration Dates

First Submitted

January 23, 2026

First Submitted That Met QC Criteria

February 1, 2026

First Posted (Actual)

February 6, 2026

Study Record Updates

Last Update Posted (Actual)

February 6, 2026

Last Update Submitted That Met QC Criteria

February 1, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • RMC/JANUARY/2025/EC07

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Healthy

Clinical Trials on autogenous tooth graft

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Poland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe