IMMEDIATE IMPLANT With Different Types of Membrane

February 2, 2026 updated by: Mansoura University

Autogenous Dentine Derived Barrier Membrane Versus Extended Platelet Rich Fibrin Membrane in Immediate Implant Placement in Posterior Mandible: a 2 Year Follow up

Forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area with immediate implants.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Al Mansurah, Egypt, 002
        • Mansoura University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Eligibility Criteria:

  1. Patients aged 18 years and older.
  2. Non-restorable mandibular molars requiring extraction and GBR for immediate implant placement.
  3. The tooth that required extraction showed no clinical or radiographic signs of acute infection.
  4. There was at least 5 mm of available bone between the superior border of the inferior alveolar canal and the root apex.
  5. At least 8 mm inter-arch space for the prosthesis.
  6. Patients were free of systemic conditions that absolutely contraindicate implant insertion.
  7. Patients with good oral hygiene.
  8. Patients capable of adhering to the mandated follow-up appointments.

Exclusion Criteria:

  1. Tobacco Smokers.
  2. Pregnancy.
  3. Patients with a history of radiation to the head and neck.
  4. Bruxism and parafunctional habits

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: immediate implant with dentin-derived membrane
Procedure: immediate implant with dentin-derived barrier membrane
immediate implant with dentin-derived barrier membrane with allograft covering any peri-implant defect and jumping gap.
Experimental: immediate implant with extended platelet rich fibrin membrane
Procedure: immediate implant with eprf membrane
immediate implant with eprf membrane with allograft covering any peri-implant defect and jumping gap.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Implant stability
Time Frame: 12 months
The implant stability was evaluated immediately postoperatively and after 3, 6, and 12 months. An Osstell Mentor device (Osstell, Savadaled, Sweden; Integration Diagnostics) was utilized to assess implant stability utilizing resonance frequency analysis (RFA). Measurements were made at 90° in four different directions in order to calculate the RFA value. The implant stability quotient (ISQ) was calculated by averaging the results for each implant.
12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mansoura University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2024

Primary Completion (Actual)

January 1, 2025

Study Completion (Actual)

January 1, 2026

Study Registration Dates

First Submitted

February 2, 2026

First Submitted That Met QC Criteria

February 2, 2026

First Posted (Actual)

February 9, 2026

Study Record Updates

Last Update Posted (Actual)

February 9, 2026

Last Update Submitted That Met QC Criteria

February 2, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • R.26.01.96

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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