Analgesic Strategies After Mastectomy: RIB vs RIB + DPIPB

February 3, 2026 updated by: İlke Dolgun, Istinye University

A Retrospective Evaluation of Systemic Analgesia, Rhomboid Intercostal Block, and Combined Rhomboid Intercostal Block With Deep Parasternal Intercostal Plane Block After Mastectomy

This retrospective observational study evaluates postoperative pain outcomes in patients undergoing elective mastectomy who received systemic analgesia, rhomboid intercostal block (RIB), or combined rhomboid intercostal block with deep parasternal intercostal plane block (RIB + DPIPB). Medical records from October 2024 to October 2025 will be reviewed. Primary outcomes include pain scores within the first 24 hours, with secondary outcomes including opioid consumption, additional analgesic requirements, patient satisfaction, and early postoperative complications. All data will be analyzed retrospectively and anonymously.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

66

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Turkey (Türkiye)
    • Merkez Mahallesi
      • Istanbul, Merkez Mahallesi, Turkey (Türkiye), 34250
        • Istinye University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

The study population consists of adult female patients aged 18-70 years who underwent elective mastectomy at a single tertiary care center between October 2024 and October 2025 and had complete postoperative pain and analgesia records available for retrospective analysis.

Description

Inclusion Criteria:

  • Female patients aged 18-70 years
  • Elective mastectomy performed between October 2024 and October 2025
  • ASA physical status I-III
  • Complete postoperative pain and analgesia records for the first 24 hours
  • Clearly documented analgesic technique (systemic analgesia, RIB, or RIB + DPIPB)

Exclusion Criteria:

  • Incomplete or missing medical records
  • Emergency mastectomy or emergency surgery
  • Reoperation within the first 24 hours postoperatively
  • Major intraoperative complications preventing standard analgesia
  • Neurological or psychiatric conditions interfering with pain assessment

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Systemic Analgesia Group
Other: Analgesic Strategy

Systemic Analgesia:

Postoperative pain was managed using standard systemic analgesic medications as part of routine clinical care.

Rhomboid Intercostal Block (RIB):

Postoperative analgesia was provided using an ultrasound-guided rhomboid intercostal block performed as part of routine clinical practice.

RIB + Deep Parasternal Intercostal Plane Block (DPIPB):

Postoperative analgesia was provided using a combination of ultrasound-guided rhomboid intercostal block and deep parasternal intercostal plane block as part of routine clinical care.
Rhomboid Intercostal Block (RIB) Group
Other: Analgesic Strategy

Systemic Analgesia:

Postoperative pain was managed using standard systemic analgesic medications as part of routine clinical care.

Rhomboid Intercostal Block (RIB):

Postoperative analgesia was provided using an ultrasound-guided rhomboid intercostal block performed as part of routine clinical practice.

RIB + Deep Parasternal Intercostal Plane Block (DPIPB):

Postoperative analgesia was provided using a combination of ultrasound-guided rhomboid intercostal block and deep parasternal intercostal plane block as part of routine clinical care.
RIB + Deep Parasternal Intercostal Plane Block (DPIPB) Group
Other: Analgesic Strategy

Systemic Analgesia:

Postoperative pain was managed using standard systemic analgesic medications as part of routine clinical care.

Rhomboid Intercostal Block (RIB):

Postoperative analgesia was provided using an ultrasound-guided rhomboid intercostal block performed as part of routine clinical practice.

RIB + Deep Parasternal Intercostal Plane Block (DPIPB):

Postoperative analgesia was provided using a combination of ultrasound-guided rhomboid intercostal block and deep parasternal intercostal plane block as part of routine clinical care.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative Pain Score (VAS)
Time Frame: Within the first 24 hours after surgery (postoperative 1, 6, 12, and 24 hours).
Postoperative pain intensity assessed using the Visual Analog Scale (VAS) based on routinely recorded clinical data.
Within the first 24 hours after surgery (postoperative 1, 6, 12, and 24 hours).

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istinye University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

February 10, 2026

Primary Completion (Estimated)

March 10, 2026

Study Completion (Estimated)

March 20, 2026

Study Registration Dates

First Submitted

February 3, 2026

First Submitted That Met QC Criteria

February 3, 2026

First Posted (Actual)

February 10, 2026

Study Record Updates

Last Update Posted (Actual)

February 10, 2026

Last Update Submitted That Met QC Criteria

February 3, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • zeki mastektomi

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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