"Evaluation of the Epidemiology of Surgically Treated Acute Traumatic Peripheral Nerve Injuries of the Upper Extremity and Their Long-Term Effects on Sensory and Motor, Functional Status, and Quality of Life"

Assessment of the Outcomes of Hand Nerve Injuries

Study Overview

• Status: Recruiting
• Conditions: Nerve Damage; Trauma Nervous System
• Intervention / Treatment: Other: Peripheral Nerve Injury Assessment

• Study Type: Observational
• Enrollment (Estimated): 100

Contacts and Locations

• Study Contact: Name: halenur yaman; Phone Number: +905418758844; Email: halenurayvaci@sdu.edu.tr

Study Locations

• Turkey (Türkiye)
  • Isparta, Turkey (Türkiye), 32200
    • Recruiting
    • Süleyman Demirel Üniversitesi Uygulama ve Araştırma Hastanesi
    • Contact: halenur yaman; Phone Number: +905418758844; Email: hale_ayvaci@hotmail.com
    • Contact: halenur yaman

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

The study population consists of adult patients presenting with acute traumatic peripheral nerve injuries of the upper extremity, including median, ulnar, radial, and combined nerve injuries, who are evaluated and managed at a tertiary care university hospital.

Description

Inclusion Criteria:

• Age 18 years and older
• Diagnosis of acute traumatic peripheral nerve injury of the upper extremity (median, ulnar, radial, or combined injuries)
• Injury requiring surgical or conservative management
• Ability to provide informed consent

Exclusion Criteria:

• History of previous peripheral nerve injury or surgery in the affected upper extremity
• Presence of central nervous system disorders affecting upper extremity function
• Severe concomitant musculoskeletal injuries preventing functional assessment
• Inability to complete clinical and functional evaluations

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
ulnar nerve	Other: Peripheral Nerve Injury Assessment; Standard clinical and functional assessment of acute traumatic peripheral nerve injuries, including motor, sensory, and functional outcome evaluations, without assignment to a specific therapeutic intervention.
median nerve	Other: Peripheral Nerve Injury Assessment; Standard clinical and functional assessment of acute traumatic peripheral nerve injuries, including motor, sensory, and functional outcome evaluations, without assignment to a specific therapeutic intervention.
ulnar and median	Other: Peripheral Nerve Injury Assessment; Standard clinical and functional assessment of acute traumatic peripheral nerve injuries, including motor, sensory, and functional outcome evaluations, without assignment to a specific therapeutic intervention.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Michigan Hand Outcomes Questionnaire (MHQ) Total Score - Injured Hand	Patient-reported hand outcomes assessed with the Michigan Hand Outcomes Questionnaire (MHQ) for the injured hand. Total score range: 0-100; higher scores indicate better hand-related outcomes.	6 months after injury

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Grip Strength of Injured Hand (Jamar Dynamometer)	Grip strength of the injured hand measured using a Jamar dynamometer (kg). Mean of 3 trials; higher values indicate greater strength.	6 months after injury
Semmes-Weinstein Monofilament Test Threshold - Injured Hand	Cutaneous pressure threshold assessed using Semmes-Weinstein monofilaments in the injured hand. Reported as monofilament level (or gram-force, if applicable); lower values indicate better sensation.	6 months after injury
Static Two-Point Discrimination - Injured Hand	Static two-point discrimination measured in millimeters (mm) in the injured hand; lower values indicate better discrimination.	6 months after injury

Collaborators and Investigators

• Sponsor: Suleyman Demirel University

Study record dates

Study Major Dates

• Study Start (Actual): July 15, 2025
• Primary Completion (Actual): May 1, 2026
• Study Completion (Estimated): May 10, 2026

Study Registration Dates

• First Submitted: January 28, 2026
• First Submitted That Met QC Criteria: February 4, 2026
• First Posted (Actual): February 11, 2026

Study Record Updates

• Last Update Posted (Actual): May 13, 2026
• Last Update Submitted That Met QC Criteria: May 8, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nervous System Diseases; Wounds and Injuries; Trauma, Nervous System
• Other Study ID Numbers: 104/15

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No