Effects of Biocidin on Oral Biofilms

March 9, 2026 updated by: OvationLab

Prospective Human Study Evaluating the Effects of Biocidin Liquid on Oral Biofilms: An Open-label Pilot Study

The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of Biocidin liquid on oral biofilms as assessed by SimplyPERIO (Spectrum Solutions, Salt Lake City, UT).

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

60

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • United States
    • Virginia
      • Richmond, Virginia, United States, 23220
        • Recruiting
        • OvationLab
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  1. Adult females or males age ≥ 25 years
  2. Ability to read and speak English
  3. Willingness to take use oral Biocidin as directed for two weeks
  4. Willingness not to change any other oral health practices for two weeks
  5. Willingness not to change dietary habits for two weeks
  6. Willingness to perform a SimplyPERIO oral microbiome test before and after the two-week Biocidin intervention

Exclusion Criteria:

  1. Current use of oral Biocidin or botanical mouthwash
  2. Use of antibiotics within the past 30 days
  3. Current use of fixed intraoral orthodontic appliances (e.g., dental braces, fixed retainers, or similar devices)
  4. Known allergies to any of the ingredients in the product
  5. Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
  6. Participants unable to provide consent

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Biocidin Liquid
Broad-spectrum botanical liquid formula
Dietary supplement: Biocidin Liquid
Broad-spectrum botanical liquid formula

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Oral Biofilm Microorganisms
Time Frame: Measured at baseline and conclusion of 2-week study
SimplyPERIO - Oral biofilm microorganism test results are categorized as "low", "medium", and "high".
Measured at baseline and conclusion of 2-week study

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

OvationLab

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 17, 2026

Primary Completion (Estimated)

April 1, 2026

Study Completion (Estimated)

April 1, 2026

Study Registration Dates

First Submitted

February 6, 2026

First Submitted That Met QC Criteria

February 6, 2026

First Posted (Actual)

February 13, 2026

Study Record Updates

Last Update Posted (Actual)

March 11, 2026

Last Update Submitted That Met QC Criteria

March 9, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • BIO-003

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

IPD will be made available on a public repository

IPD Sharing Time Frame

IPD will be made available indefinitely following analysis

IPD Sharing Access Criteria

IPD will be available upon reasonable request

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Biofilm

Clinical Trials on Biocidin Liquid

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Czech Republic

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe