Effect of Digitally Supported Medical Nutrition Therapy on Left Ventricular Ejection Fraction in Patients With ST-Elevation Myocardial Infarction

February 16, 2026 updated by: Saglik Bilimleri Universitesi

Effect of Digitally Supported Medical Nutrition Therapy on Left Ventricular Ejection Fraction in Patients With ST-Elevation Myocardial Infarction: A Randomized Controlled Trial

This study is designed to investigate the effect of a nutrition program supported by digital content on heart function in patients who have experienced a heart attack with ST-elevation. Participants will receive personalized dietary guidance and digital support materials for three months. The main goal is to determine whether this digital support materials can improve heart pumping function (measured by left ventricular ejection fraction). Participation involves following the dietary program and undergoing heart function measurements at the beginning, after one months and after three months.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

200

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Individuals aged 19-65 who have fully completed the voluntary consent form
  • Being of normal weight (BMI 18.5-24.9 kg/m²) or obese (30-34.99 kg/m²)
  • Having suffered a heart attack with ST elevation (STEMI)
  • To be enrolled in the study within the first 72 hours after hospital admission
  • To be willing to participate in a follow-up period of at least 3 months

Exclusion Criteria:

  • Those who did not sign the voluntary consent form
  • Individuals aged over 65
  • Weight loss exceeding 5% in the last 3 months
  • Those with malignancy, chronic renal failure or severe systemic disease
  • Patients unable to complete the questionnaires due to severe cognitive impairment
  • Those who have previously received nutrition education or eating awareness training

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
No Intervention: Standard Dietary Care / Control
Participants in this group receive standard dietary care as routinely provided to patients after ST-elevation myocardial infarction, without additional digital content support. Heart function (LVEF) will be measured at baseline, 1 month, and 3 months.
Experimental: Digital Content-Supported Nutrition Therapy
Participants in this group receive a personalized medical nutrition therapy program supported by digital content, including educational materials, meal planning guides, and remote support. The program lasts 3 months, with follow-up visits at baseline, 1 month, and 3 months. Heart function (LVEF) will be measured at each time point.
Behavioral: Digital Content-Supported Medical Nutrition Therapy
Participants receive a personalized medical nutrition therapy program supported by digital content. The program includes educational materials, meal planning guides, and remote support. The intervention lasts 3 months, with follow-up visits at baseline, 1 month, and 3 months. Heart function (LVEF) will be measured at each time point.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Left Ventricular Ejection Fraction (LVEF)
Time Frame: Baseline, 1 month, 3 months
Left ventricular ejection fraction will be measured using echocardiography at baseline, 1 month, and 3 months to evaluate the effect of digital content-supported medical nutrition therapy.
Baseline, 1 month, 3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saglik Bilimleri Universitesi

Collaborators

Ondokuz Mayis University Training and Research Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 30, 2025

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Study Registration Dates

First Submitted

February 16, 2026

First Submitted That Met QC Criteria

February 16, 2026

First Posted (Actual)

February 23, 2026

Study Record Updates

Last Update Posted (Actual)

February 23, 2026

Last Update Submitted That Met QC Criteria

February 16, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2025/012

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on ST-elevation Myocardial Infarction (STEMI)

Clinical Trials on Digital Content-Supported Medical Nutrition Therapy

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe