Artificial Intelligence-Based Cognitive Training in Patients With Stroke (AICoRe-Stroke)

March 1, 2026 updated by: Omima Alaa Eldin Hussein

Effect of Artificial Intelligence-Based Training on Cognitive Functions in Patients With Stroke

This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke?

The aims of this study:

To investigate the efficacy of AI application-based training on cognitive function in stroke patients.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
    • Egypt
      • Cairo, Egypt, Egypt, 62517
        • Recruiting
        • Physical therapy- Cairo University
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Patient's age will range from 45- 60 years.

    • Diagnosis of stroke in the chronic stage (≥3 months post-onset).
    • Presence of cognitive impairment confirmed by a Montreal Cognitive Assessment (MoCA) score ≤ 26.
    • Medically stable and able to follow instructions.
    • patients with memory deficits following stroke

Exclusion Criteria:

- Patients will be excluded if they have:

  • Severe visual, hearing, or speech impairments prevent participation.
  • History of other neurological or psychiatric disorders.
  • Unstable cardiovascular or systemic disease.
  • Severe depression (Beck Depression Inventory > 29).

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: AI-Based Cognitive Training
Participants receive artificial intelligence-based cognitive training in stroke patients. The AI program is designed to target multiple cognitive domains including attention, memory, executive function, and processing speed.
Device: cognifit Mobile Application for Cognitive Training
A structured artificial intelligence-based cognitive training program targeting attention, memory, executive function, and processing speed in patients with stroke. The program provides adaptive, individualized exercises based on participant performance.
Active Comparator: Conventional Physical Therapy
Participants receive a conventional rehabilitation program consisting of aerobic exercises, relaxation exercises, and traditional paper-based cognitive exercises, in addition to standard physical therapy.
Behavioral: Conventional Cognitive Rehabilitation
A structured conventional rehabilitation program consisting of aerobic exercises, relaxation exercises, and traditional paper-based cognitive exercises for patients with stroke. The duration and frequency of treatment are matched to the experimental group.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in Cognitive Function
Time Frame: Baseline and 6 weeks post-intervention

Change in Global Cognitive Function Measured by the Montreal Cognitive Assessment (MoCA) Global cognitive function will be assessed using the Montreal Cognitive Assessment (MoCA), a one-page, 30-point cognitive screening tool that evaluates attention, memory, executive function, language, visuospatial abilities, abstraction, calculation, and orientation. The test takes approximately 10 minutes to administer.

Scores range from 0 to 30, with higher scores indicating better cognitive function. A score of less than 26 indicates cognitive impairment.
Baseline and 6 weeks post-intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Omima Alaa Eldin Hussein

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2026

Primary Completion (Actual)

February 1, 2026

Study Completion (Estimated)

June 6, 2026

Study Registration Dates

First Submitted

February 19, 2026

First Submitted That Met QC Criteria

March 1, 2026

First Posted (Actual)

March 5, 2026

Study Record Updates

Last Update Posted (Actual)

March 5, 2026

Last Update Submitted That Met QC Criteria

March 1, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • P.T.REC/012/006268

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

Yes

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Stroke

Clinical Trials on cognifit Mobile Application for Cognitive Training

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Singapore

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe