Application and Impact Assessment of Ultrasound Super-Resolution Blood Flow Imaging (URM) in Patients With Renal Failure (URM)

March 16, 2026 updated by: Ma Zhe
The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease staging and monitoring treatment response.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

150

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Shandong
      • Jinan, Shandong, China
        • The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:① Clinically diagnosed with acute or chronic renal failure; ② Complete laboratory test results and ultrasound images are available.

Exclusion Criteria:① Concurrent severe organ failure; ② Poor image quality; ③ History of renal surgery; ④ Pregnant or breastfeeding women.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Patients with acute kidney failure
Diagnostic test: Ultrasound super-resolution blood flow imaging
The primary objective is to examine the correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory markers of renal function (eGFR, Scr)
Other Names:
  • Patients with acute kidney failure
  • Patients with chronic kidney failure
Experimental: Patients with chronic kidney failure
Diagnostic test: Ultrasound super-resolution blood flow imaging
The primary objective is to examine the correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory markers of renal function (eGFR, Scr)
Other Names:
  • Patients with acute kidney failure
  • Patients with chronic kidney failure

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory renal function markers (eGFR, Scr)
Time Frame: From enrollment to the end of treatment at 14 days
From enrollment to the end of treatment at 14 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ma Zhe

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2024

Primary Completion (Actual)

October 1, 2025

Study Completion (Actual)

March 1, 2026

Study Registration Dates

First Submitted

March 16, 2026

First Submitted That Met QC Criteria

March 16, 2026

First Posted (Actual)

March 20, 2026

Study Record Updates

Last Update Posted (Actual)

March 20, 2026

Last Update Submitted That Met QC Criteria

March 16, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • YXLL-KY-2026(007)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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