Integrated Trunk Stabilization With Osteoarthritis Rehabilitation in Knee-Spine Syndrome

April 30, 2026 updated by: Riphah International University

Integrating Trunk Stabilization Exercises With Conventional Rehabilitation Protocol for Osteoarthritis in Patients With Knee-Spine Syndrome

This study aims to evaluate the effects of integrating trunk stabilization exercises with conventional rehabilitation in patients with knee-spine syndrome. It further examines whether improving trunk stability can reduce knee pain and enhance functional outcomes in knee osteoarthritis

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

This study aims to evaluate the effects of integrating trunk stabilization exercises with conventional rehabilitation protocols for patients with knee-spine syndrome. It seeks to determine whether improving trunk stability can positively influence knee joint mechanics, leading to a reduction in knee pain and improvements in physical function, mobility, and overall functional performance in individuals with knee osteoarthritis. The findings may support a more comprehensive rehabilitation approach addressing both spinal and knee involvement in osteoarthritis management.

Study Type

Interventional

Enrollment (Estimated)

70

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Age 40-60 years
  • Both Genders
  • Bilateral Knee osteoarthritis diagnosed according to the American College of Rheumatology Clinical Classification system
  • Kellgren & Lawrence grade 2 and 3 with complaint of pain, crepitations, stiffness and bony enlargement
  • History of backpain for the past 3 months with no complaint of radiating pain
  • Able to walk independently/unaided

Exclusion Criteria:

  • Kellgren & Lawrence grade 4
  • Intra-articular corticosteroid injections in the last 3 months or hyaluronic knee injection in the previous 6 months.
  • History of lower limb or lumbar trauma/surgery, presence of fracture or deformity, or planned surgery within the study period
  • Lumbar pathologies, for example, spondylolisthesis, ankylosing spondylitis, or any diagnosed severe cardiovascular, pulmonary, neurological, or psychological disease or impairment except lumbar spondylosis
  • BMI>30
  • Presence of infection, cauda equina syndrome, or meningitis

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Trunk Stabilization exercises with conventional Rehab

The intervention will include the conventional knee osteoarthritis rehabilitation protocol comprising mobilization, stretching, and strengthening exercises, along with the following trunk stabilization exercises performed for 6 repetition followed by 30 second rest :

  1. Prone extension
  2. Back bridge
  3. Unilateral back bridge
  4. Sideways step-up
  5. Bird dog
Other: Trunk Stabilization exercises with conventional Rehab
The protocol for will be followed for 6 weeks, where individuals will perform trunk stabilization exercises with conventional rehabilitation for knee osteoarthritis.
Other: Conventional Rehabilitation
The conventional rehabilitation protocol for knee osteoarthritis included Maitland's mobilization performed at a rate of 2-3 oscillations per second for 2 minutes, followed by stretching exercises held for 30 seconds across three sets. Muscle strengthening exercises were also incorporated, consisting of 10 repetitions with a 15-second hold, performed over four sets.
Other: Conventional Rehabilitation
The protocol for will be followed for 6 weeks, where conventional rehabilitation for knee osteoarthritis will be implemented.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Visual Analogue Scale
Time Frame: 6 weeks
The Visual Analog Scale (VAS) is a simple and reliable tool for assessing pain intensity on a continuous visual scale. The extreme limits of pain are represented by the straight line's ends, where 0 indicates no pain, and 10 indicates the worst pain a person has ever felt.
6 weeks
Western Ontario and McMaster Universities Arthritis Index (WOMAC)
Time Frame: 6 weeks
It is widely used in the evaluation of knee osteoarthritis to assess activities of daily living, functional mobility, gait, general health, and quality of life. It has 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). The scores range from 0 to 4 for each subscale. The score ranges from 0 to 96, where zero indicates no pain, stiffness, and functional limitation. Higher scores indicate worse pain, stiffness, and functional limitation.
6 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Range Of motion (ROM)
Time Frame: 6 weeks
A Goniometer is used to measure active and passive ROM for knee flexion and extension while the patient lies supine
6 weeks
Flexicurve (Lumbar Range of motion)
Time Frame: 6 weeks
Flexicurve is a flexible plastic-coated metal ruler molded to the lumbar spine's sagittal contour (typically T12 to S1) to non-invasively measure lordosis angle via traced perpendicular heights, serving as a radiation-free alternative to X-rays
6 weeks
Time-Up-and-Go (TUG)
Time Frame: 6 weeks
This test is a widely used assessment of functional mobility, particularly in patients with knee osteoarthritis. The test measures the total time it takes for a patient to stand up from a chair, walk 3 meters at a comfortable pace, turn around, walk back to the chair, and sit down. A shorter time indicates better functional performance
6 weeks
Oswestry Disability Index (ODI)
Time Frame: 6 weeks
It is a questionnaire that gives a subjective percentage score of level of function/disability in activities of daily living of patients with low back pain. It contains 10 items, each scored from 0 to 5, with the total score converted to a percentage ranging from 0% to 100%. Higher percentages indicate greater disability, i.e., worse outcomes, while lower percentages indicate less disability/better outcomes.
6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Suman Sheraz, PhD, Riphah International University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

April 1, 2026

Primary Completion (Estimated)

July 15, 2026

Study Completion (Estimated)

August 15, 2026

Study Registration Dates

First Submitted

March 16, 2026

First Submitted That Met QC Criteria

March 16, 2026

First Posted (Actual)

March 20, 2026

Study Record Updates

Last Update Posted (Actual)

May 6, 2026

Last Update Submitted That Met QC Criteria

April 30, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Tooba Rauf

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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