- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07484880
Effectiveness of D'Antibiotika Academy Board Game for Dental Education
Evaluating the Effectiveness of D'Antibiotika Academy Board Game on Antibiotics and Bacteria Knowledge: A Randomized Crossover Study Among Dental Students
The goal of this clinical trial study is to evaluate the effectiveness of a board game-based serious game as a learning strategy to improve knowledge and study motivation on antibiotics and bacteria topics in undergraduate dental students at Faculty of Dentistry, Universitas Indonesia.
The main questions it aims to answer are:
- Does the "D'Antibiotika Academy" board game lead to higher post-test scores compared to traditional handout-based learning?
- Does the board game improve students' study motivation on antibiotics and bacteria topic?
Researchers will compare the board game intervention group to the traditional handout (control) group to see if the game-based approach provides superior learning outcomes and higher student engagement.
Participants will:
- Complete a pre-test to measure their baseline knowledge of bacteria and antibiotics.
- Participate in a learning session using either the "D'Antibiotika Academy" board game or a conventional handout.
- Complete a post-test 1 and post-test 2 immediately after the session to measure immediate knowledge gain.
- Switch groups (crossover) after a washout period to ensure all participants experience both methods.
- Complete a study motivation questionnaire after the completion of the sessions.
Study Overview
Status
Intervention / Treatment
Detailed Description
Study Design and Setting:
This study was a single-blind crossover randomized controlled trial conducted at Universitas Indonesia from September to December 2025. The participants (n=101) were undergraduate dental students from the Faculty of Dentistry, Universitas Indonesia. Participants were stratified by academic year and then assigned to either the HO-BG (Handout then Board Game) or BG-HO (Board Game then Handout) group using stratified random sampling. Ethical approval was secured from the Dental Research Ethics Committee, Universitas Indonesia (54/Ethical Approval/FKGUI.IX/2025).
Interventions:
The study compared two learning media with identical content regarding antibiotic classification, mechanisms of action, resistance, selection, bacterial classification, and quorum sensing:
- Board Game (D'Antibiotika Academy): An interactive game played in groups of 4-5 students.
- Handout: A digital text-based learning material for independent study.
Study Protocol:
- Baseline: All participants completed a pre-test to establish baseline knowledge.
- Phase 1: The HO-BG group studied via handout independently, while the BG-HO group played the board game in a supervised two-hour session at the Health Sciences Cluster Building. Phase 1 concluded with Post-test 1.
- Washout Period: A one-week washout period was implemented to minimize carryover effects.
- Phase 2 (Crossover): The groups switched interventions. The HO-BG group played the board game, and the BG-HO group accessed the handout. After one week, all participants completed Post-test 2.
Assessment Tools:
- Knowledge Test: 40 shuffled multiple-choice questions (20 questions for antibiotic topic and 20 questions for bacteria topic) administered via Google Forms (Max score: 100).
- Motivation Questionnaire: At the study's conclusion, participants completed the Instructional Materials Motivational Survey (IMMS) based on the ARCS Model (Attention, Relevance, Confidence, and Satisfaction). Each participant evaluated both the board game and handout methods.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
Jakarta Special Capital Region
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Jakarta Pusat, Jakarta Special Capital Region, Indonesia, 10430
- Faculty of Dentistry Universitas Indonesia
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Undergraduate dental students at the Faculty of Dentistry, Universitas Indonesia, from the class of 2022, 2023, and 2025.
- Students who demonstrate a clear understanding of the study's explanation provided by the researchers and are willing to participate by signing the informed consent form.
- Students who are committed to participating in all research sessions and procedures until completion
Exclusion Criteria:
- Students who are unable to participate in the entire research sequence from beginning to end.
- Students who withdraw their participation at any point during the study period.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: HO-BG Group (Handout then Board Game)
Participants in this arm are provided with a digital text-based Handout-based learning during intervention phase 1 followed by board game learning during intervention phase 1
|
A serious board game designed for dental students to learn about antibiotic classification, mechanisms of action, resistance, and bacterial classification.
The intervention is delivered in a 120-minute in two sessions supervised interactive group session.
A digital text-based learning material containing identical scientific content to the D'Antibiotika Academy board game.
Participants access and study the material independently
|
|
Experimental: BG-HO Group (Board Game then Handout)
Participants in this arm are provided with a Board game learning during intervention phase 1, followed by handout-based learning during intervention phase 2
|
A serious board game designed for dental students to learn about antibiotic classification, mechanisms of action, resistance, and bacterial classification.
The intervention is delivered in a 120-minute in two sessions supervised interactive group session.
A digital text-based learning material containing identical scientific content to the D'Antibiotika Academy board game.
Participants access and study the material independently
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Knowledge Score
Time Frame: -) [Day 1] baseline (pre-test) -) [Days 2-3] Intervention phase 1 (2 days), followed by Post-test 1 -) [Days 4-10] Washout periods (up to 7 days) -) [Days 11-12] Intervention Phase 2 (2 days), followed by Post-test 2
|
A knowledge assessment consisting of 40 multiple-choice questions, with 20 questions dedicated to antibiotic topics and 20 questions to bacterial topics.
The maximum score is 100, where higher scores indicate better knowledge acquisition.
This assessment was used on Pre-Test, Post-Test 1 and Post-Test 2.
|
-) [Day 1] baseline (pre-test) -) [Days 2-3] Intervention phase 1 (2 days), followed by Post-test 1 -) [Days 4-10] Washout periods (up to 7 days) -) [Days 11-12] Intervention Phase 2 (2 days), followed by Post-test 2
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Learning Motivation Score (IMMS Questionnaire)
Time Frame: at study completion (Days 12-14)
|
Evaluation of student motivation using the Instructional Materials Motivational Survey (IMMS) based on the ARCS Model (Attention, Relevance, Confidence, and Satisfaction).
The survey uses a 5-point Likert scale, where higher scores represent higher levels of motivation toward the learning method.
The questionnaire is administered to evaluate both the handout and the board game interventions.
The questionnaire is administered once upon completion of all study sessions.
|
at study completion (Days 12-14)
|
Collaborators and Investigators
Sponsor
Publications and helpful links
General Publications
- Holz M, Naavaal S, Stilianoudakis S, Carrico C, Byrne BE, Myers GL. Antibiotics and antimicrobial resistance: Evaluation of the knowledge, attitude, and perception among students and faculty within US dental schools. J Dent Educ. 2021 Mar;85(3):383-391. doi: 10.1002/jdd.12445. Epub 2020 Oct 12.
- AboAlSamh A, Alhussain A, Alanazi N, Alahmari R, Shaheen N, Adlan A. Dental Students' Knowledge and Attitudes towards Antibiotic Prescribing Guidelines in Riyadh, Saudi Arabia. Pharmacy (Basel). 2018 May 7;6(2):42. doi: 10.3390/pharmacy6020042.
- Valente P, Lora PS, Landell MF, Schiefelbein CS, Girardi FM, Souza Ldos R, Zanonato A, Scroferneker ML. A game for teaching antimicrobial mechanisms of action. Med Teach. 2009 Sep;31(9):e383-92. doi: 10.1080/01421590802637958.
- Karbownik MS, Wiktorowska-Owczarek A, Kowalczyk E, Kwarta P, Mokros L, Pietras T. Board game versus lecture-based seminar in the teaching of pharmacology of antimicrobial drugs--a randomized controlled trial. FEMS Microbiol Lett. 2016 Apr;363(7):fnw045. doi: 10.1093/femsle/fnw045. Epub 2016 Feb 23.
- Arayapisit T, Pojmonpiti D, Dansirisomboon K, Jitverananrangsri K, Poosontipong D, Sipiyaruk K. An educational board game for learning orofacial spaces: An experimental study comparing collaborative and competitive approaches. Anat Sci Educ. 2023 Jul-Aug;16(4):666-676. doi: 10.1002/ase.2257. Epub 2023 Feb 5.
- Rutledge C, Walsh CM, Swinger N, Auerbach M, Castro D, Dewan M, Khattab M, Rake A, Harwayne-Gidansky I, Raymond TT, Maa T, Chang TP; Quality Cardiopulmonary Resuscitation (QCPR) leaderboard investigators of the International Network for Simulation-based Pediatric Innovation, Research, and Education (INSPIRE). Gamification in Action: Theoretical and Practical Considerations for Medical Educators. Acad Med. 2018 Jul;93(7):1014-1020. doi: 10.1097/ACM.0000000000002183.
- Imwattana K, Methawirune A, Voralakkulchai I, Ngamskulrungroj P. BactoBattle: a game-based learning companion for medical bacteriology. Access Microbiol. 2023 Jun 26;5(6):acmi000608.v3. doi: 10.1099/acmi.0.000608.v3. eCollection 2023.
- Amir LR, Leonardy IC, Dewatmoko SN, Yanuar R, Suniarti DF, Idrus E, Sipiyaruk K, Puspitawati R. Serious game as oral histology learning strategy for undergraduate dental students; crossover randomized controlled trial. BMC Oral Health. 2023 Aug 23;23(1):585. doi: 10.1186/s12903-023-03286-3.
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 54/Ethical Appr/FKGUI/IX/2025
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
IPD Plan Description
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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