Fatigue and Mental Well-Being in MS Patients(Multiple Sclerosis) (MS)

April 15, 2026 updated by: Sevgi DEMIR CAM, Artvin Coruh University

Evaluation of the Effect of Quran Recitation on Fatigue and Mental Well-Being in MS Patients: A Randomized Controlled Trial

This study will be conducted to evaluate the effects of Quran recital on fatigue and mental well-being in patients with multiple sclerosis.

Hypotheses:

  1. Quran recital reduces fatigue in MS patients.
  2. Quran recital increases mental well-being in MS patients. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

50 patients who meet the inclusion criteria and voluntarily agree to participate in the study will be determined. These patients will be informed about the study and their consent will be obtained. These patients will then be randomized into the Quran recital group and the control group. Personal and contact information of the patients will be recorded and pre-test forms will be applied. The Quran recital group will be asked to listen to the Quran for half an hour with an mp3 player given to them 3 days a week (Monday-Wednesday-Friday) between 21:00-22:00 and this practice will be continued for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.

Study Type

Interventional

Enrollment (Estimated)

52

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Turkey (Türkiye)
      • Van, Turkey (Türkiye), 65200
        • Recruiting
        • Van Yüzüncü Yıl University Dursun Odabaş Medical Center
        • Contact:
          • Yavuz Üren, Asst. Prof

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Having been diagnosed with Multiple Sclerosis at least 6 months ago
  2. Being between the ages of 18-80
  3. Agreeing to participate in the research
  4. Not having any obstacles to wearing headphones
  5. Not having any hearing problems

Exclusion Criteria:

  1. Those with major psychiatric disorders
  2. Those with any obstacle to communication

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Single Group Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Experimental group
The Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21:00-22:00 3 days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The final test measurements will be made at the end of the 4th week by interviewing the patients at the hospital.
Behavioral: Quran recital
The Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21.00-22.00 three days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks.
No Intervention: Control group
Personal and contact information about the patients will be recorded and pre-test forms will be applied. The control group will continue their routine treatment and care and no additional intervention will be applied. Post-test measurements will be made by meeting with the patients at the hospital at the end of the 4th week.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fatigue Impact
Time Frame: 1 mount
The Fatigue Impact Scale (FIS)
1 mount

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fatigue Severity Warwick-Edinburgh Mental Well-Being Scale
Time Frame: 1 mount
The Fatigue Severity Scale (FSS)
1 mount

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Artvin Coruh University

Investigators

  • Study Chair: Sevgi Demir Cam, Asst. Prof, Artvin Çoruh University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 9, 2025

Primary Completion (Estimated)

May 15, 2026

Study Completion (Estimated)

May 15, 2026

Study Registration Dates

First Submitted

July 4, 2025

First Submitted That Met QC Criteria

April 15, 2026

First Posted (Actual)

April 22, 2026

Study Record Updates

Last Update Posted (Actual)

April 22, 2026

Last Update Submitted That Met QC Criteria

April 15, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MS-Kuran

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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