IVC Collapsibility Index in Lumbar Stabilization Surgery

April 17, 2026 updated by: Şeyma Yüksel Ayar, Trabzon Kanuni Education and Research Hospital

Hemodynamic Assessment Using the Inferior Vena Cava Collapsibility Index in Patients Undergoing Lumbar Stabilization Surgery

This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia. The IVC diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points. Hemodynamic parameters such as blood pressure and heart rate will also be recorded. The study seeks to determine whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and hemodynamic changes during lumbar spine surgery.

Study Overview

Status

Recruiting

Conditions

Detailed Description

his prospective study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia in the prone position. The inferior vena cava diameter will be measured using ultrasonography at different perioperative time points, including the preoperative period, after induction of anesthesia, and before extubation.

The IVC diameter and collapsibility index will be recorded and analyzed to assess changes in intravascular volume status during the perioperative period. In addition to ultrasonographic measurements, hemodynamic parameters such as blood pressure and heart rate will be monitored and recorded.

The study aims to investigate whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and perioperative hemodynamic changes in patients undergoing lumbar spine surgery.

Study Type

Observational

Enrollment (Estimated)

128

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Turkey (Türkiye)
      • Trabzon, Turkey (Türkiye), 61080
        • Recruiting
        • Trabzon University Faculty of Medicine Kanunı Training and Research Hospital ,Trabzon
      • Trabzon, Turkey (Türkiye), 61080
        • Recruiting
        • Trabzon University Faculty of Medicine, Kanuni Training and Research Hospital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adult patients (≥18 years) scheduled for elective lumbar spine stabilization surgery under general anesthesia at Trabzon University Faculty of Medicine Hospital will be included in this study. All participants will be classified as ASA physical status I-II-III and will undergo surgery in the prone position. Inferior vena cava (IVC) diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points.

Description

Inclusion Criteria:

  • Age ≥ 18 years
  • Patients classified as ASA physical status I-II-III
  • Patients scheduled for elective lumbar spine stabilization surgery under general anesthesia
  • Ability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
  • Provision of written informed consent

Exclusion Criteria:

  • Age younger than 18 years

    • Emergency surgery
    • American Society of Anesthesiologists (ASA) physical status IV
    • Patients undergoing revision lumbar stabilization surgery
    • Baseline systolic blood pressure >180 mmHg or <90 mmHg
    • Heart failure with ejection fraction (EF) <40%
    • Pulmonary artery pressure (PAP) >40 mmHg
    • Presence of intra-abdominal mass, ascites, or increased intra-abdominal pressure
    • Body mass index (BMI) >30 kg/m²
    • Pregnancy
    • Patients with neurological or psychiatric disorders
    • Inability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
    • Refusal to provide written informed consent

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Patients Undergoing Lumbar Spine Surgery
Adult patients undergoing elective lumbar spine stabilization surgery under general anesthesia in the prone position. Inferior vena cava (IVC) diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points (preoperative period, after induction of anesthesia, and before extubation). Hemodynamic parameters such as blood pressure and heart rate will also be recorded.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Inferior Vena Cava Collapsibility Index
Time Frame: Perioperative period (preoperative assessment, after anesthesia induction, and before extubation)
The inferior vena cava (IVC) collapsibility index will be measured using ultrasonography at predefined perioperative time points (preoperative period, after induction of general anesthesia, and before extubation) in patients undergoing elective lumbar spine surgery in the prone position.
Perioperative period (preoperative assessment, after anesthesia induction, and before extubation)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Intraoperative Hypotension Incidence
Time Frame: During the intraoperative period
The occurrence of intraoperative hypotension during lumbar spine surgery under general anesthesia will be recorded. Hypotension will be defined as mean arterial pressure below 65 mmHg.
During the intraoperative period

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Trabzon Kanuni Education and Research Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 15, 2026

Primary Completion (Actual)

February 15, 2026

Study Completion (Estimated)

July 15, 2026

Study Registration Dates

First Submitted

April 17, 2026

First Submitted That Met QC Criteria

April 17, 2026

First Posted (Actual)

April 23, 2026

Study Record Updates

Last Update Posted (Actual)

April 23, 2026

Last Update Submitted That Met QC Criteria

April 17, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 10496660-2026/25031

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Individual participant data will not be publicly shared because the dataset contains patient-level clinical information collected during routine clinical care. Data may be available from the investigators upon reasonable request and with approval from the institutional ethics committee.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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