- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07322562
Effects of Music Therapy on Anesthetic Requirements and Hemodynamic Parameters
February 16, 2026 updated by: mediha turktan, Cukurova University
Effects of Music Therapy on Anesthetic Requirements and Hemodynamic Parameters in Thoracic Surgery Patients
Music therapy has been reported to reduce analgesic and anesthetic requirements, but evidence in thoracic surgery remains limited.
This prospective observational study aimed to evaluate the effects of different music types on hemodynamic stability and anesthetic consumption in patients undergoing thoracic surgery.
Study Overview
Status
Completed
Intervention / Treatment
Detailed Description
After institutional ethics approval and written informed consent, 159 adult patients (ASA I-III) scheduled for elective thoracic surgery under general anesthesia were enrolled.
Patients were randomized by sealed-envelope method into three groups: Group T (Sufi music), Group B (Classical Western music), and Group C (control, no music).
Music was delivered via over-ear headphones from induction until the end of surgery.
Sedation was evaluated using the Riker Sedation-Agitation Scale (RSAS), and pain using the Visual Analog Scale (VAS).
Hemodynamic variables, anesthetic agent consumption, and postoperative recovery parameters were recorded.
Study Type
Observational
Enrollment (Actual)
159
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Adana
-
Adana, Adana, Turkey (Türkiye), 01380
- Cukurova University Faculty of Medicine Anesthesiology Department
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Sampling Method
Probability Sample
Study Population
All patients who will undergo thoracic surgery under general anesthesia and meet the criteria of being over 18 years of age
Description
Inclusion Criteria:
- Age 18 and over,
- American Society of Anesthesiologists (ASA) classification I-III,
- No hearing acuity,
- Volunteer to participate in the study,
- Cooperative and oriented,
- No history of psychiatric illness and/or psychiatric medication use,
Exclusion Criteria:
- Patients who were under 18 years,
- ASA classification >III,
- had hearing loss,
- had a psychiatric diagnosis and/or were taking antipsychotic/antidepressant/mood stabilizer medications,
- were uncooperative (dementia, mental retardation, etc.),
- Major complications during the intraoperative or postoperative period, (respiratory failure, hemodynamic instability, hypoxia, serious arrhythmia, cardiac arrest, etc.)
- Emergency surgery,
- had a history of alcohol or drug abuse,
- did not speak Turkish,
- did not consent to participate in the study.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Group 1: Sufi music group
In the sufi music group, sufi music was played through over-ear headphones; the volume was adjusted based on patient comfort and confirmed with the patient.
Music playback was initiated alongside routine monitoring and continued throughout the surgery, ending when the patient was transferred to the stretcher after extubation.
|
In the music groups, music was played through over-ear headphones; the volume was adjusted based on patient comfort and confirmed with the patient.
Music playback was initiated alongside routine monitoring and continued throughout the surgery, ending when the patient was transferred to the stretcher after extubation.
For infection control purposes, headphone sponges were changed for each patient.
|
|
Group 2: Classical Western music group
In the classical Western music group, music was played through over-ear headphones; the volume was adjusted based on patient comfort and confirmed with the patient.
Music playback was initiated alongside routine monitoring and continued throughout the surgery, ending when the patient was transferred to the stretcher after extubation.
|
In the music groups, music was played through over-ear headphones; the volume was adjusted based on patient comfort and confirmed with the patient.
Music playback was initiated alongside routine monitoring and continued throughout the surgery, ending when the patient was transferred to the stretcher after extubation.
For infection control purposes, headphone sponges were changed for each patient.
|
|
Group 3: no music group
In the no music group, the patient was not allowed to listen to any type of music during surgery.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
anesthetic consumption
Time Frame: during surgery
|
desfluran consumption during surgery (mL)
|
during surgery
|
|
anesthetic consumption
Time Frame: during induction of anesthesia
|
Induction propofol dose (mg)
|
during induction of anesthesia
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
hemodynamic parameters
Time Frame: during surgery, 48 hour after surgery
|
systolic blood pressure (mmHg)
|
during surgery, 48 hour after surgery
|
|
hemodynamic parameters
Time Frame: during surgery, 48 hour after surgery
|
diastolic blood pressure (mmHg)
|
during surgery, 48 hour after surgery
|
|
hemodynamic parameters
Time Frame: during surgery, 48 hour after surgery
|
mean arterial pressure (mmHg)
|
during surgery, 48 hour after surgery
|
|
hemodynamic parameters
Time Frame: during surgery, 48 hour after surgery
|
heart rate (beats/min)
|
during surgery, 48 hour after surgery
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Mediha Turktan, M.D., Çukurova University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
October 1, 2025
Primary Completion (Actual)
December 31, 2025
Study Completion (Actual)
December 31, 2025
Study Registration Dates
First Submitted
December 15, 2025
First Submitted That Met QC Criteria
December 29, 2025
First Posted (Actual)
January 7, 2026
Study Record Updates
Last Update Posted (Actual)
February 17, 2026
Last Update Submitted That Met QC Criteria
February 16, 2026
Last Verified
October 1, 2025
More Information
Terms related to this study
Other Study ID Numbers
- music01
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Thoracic Surgery
-
Maquet Cardiopulmonary GmbHNAMSATerminatedCardiac Surgery | Cardiopulmonary Bypass | Thoracic Surgery | Vascular SurgerySpain, Italy
-
Vanderbilt UniversityEdwards LifesciencesCompletedCardiac Surgery | Thoracic Surgery | Heart Surgery | Heart Transplant
-
Centre hospitalier de l'Université de Montréal...RecruitingThoracic Surgery | Video-assisted Thoracic Surgery | Robotic-assisted Thoracic SurgeryCanada
-
Academisch Medisch Centrum - Universiteit van Amsterdam...CompletedCardiac Surgery | Cardiopulmonary Bypass | Thoracic SurgeryNetherlands
-
Federal University of Rio Grande do SulRecruiting
-
Association Pro-arteUniversity Hospital, GrenobleCompleted
-
Mayo ClinicTerminatedThoracic Surgery | Surgery, ThoracicUnited States
-
Örebro University, SwedenCompleted
-
Hospices Civils de LyonCompletedSurgery | ThoracicFrance
-
Hospital de Clinicas de Porto AlegreUNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL (UFRGS)Completed
Clinical Trials on music therapy during surgery
-
University Tunis El ManarNot yet recruiting
-
University of UlmUniversity Hospital UlmCompleted
-
Azienda Ospedaliera Città della Salute e della...Completed
-
Cliniques universitaires Saint-Luc- Université...Completed
-
Biruni UniversityCompletedPregnancy | Maternal Anxiety | Fetal Well-BeingTurkey (Türkiye)
-
Elena TessitoreRecruitingRehabilitation ExerciseSwitzerland
-
Institut Claudius RegaudRecruiting
-
Afyonkarahisar Health Sciences UniversityCompleted
-
Hasselt UniversityUniversity Ghent; Revalidatie & MS Centrum Overpelt; National MS Center MelsbroekCompleted
-
Medical University of South CarolinaTerminatedIntubation | Mechanical Ventilation | Music Therapy | Spontaneous Breathing TrialUnited States