- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT03431376
Potato Consumption and Risk of Hypertension
12. februar 2018 opdateret af: Yu Zhang, Zhejiang University
Potato Consumption Is Prospectively Associated With Risk of Hypertension: An 11.3-year Longitudinal Cohort Study
Government has popularized potatoes as a major staple food in China.
Potato, a potassium-rich food with high glycemic responses after consumption, exhibits unclear effects on hypertension.
In this study, the investigators aimed to examine the association between potato consumption and hypertension risk among Chinese people.
Studieoversigt
Status
Afsluttet
Betingelser
Detaljeret beskrivelse
Potato is considered as a superior crop due to its significant nutritive value and great production yield.
China is the largest potato producer with a quarter of world production, followed by India, Russia, and USA.
The potato production as well as consumption has enhanced in developing countries while continuously declined in developed countries during the last decade.
The investigators therefore explored the prospective associations of consumption of total potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes with the risk of hypertension in general people of the China Health and Nutrition Survey (CHNS) cohort study from 1989 to 2011.
A total of 11,763 participants (≥20 years old) who were free of hypertension at baseline were enrolled from CHNS Cohort study.
Cox proportional hazards regression models were used to estimate the associations after adjusting for potential confounders.
This study provides new evidence on the association of various potato consumption with the incidence of hypertension in China.
As urbanization accelerates across the whole domain of China, the tendency of transition to Western-style diets and lifestyles appears continuously and steeply growing.
More and more potatoes will be consumed as processed potato products including potatoes chips and French fries, which may be a potential risk factor of hypertension occurrence.
Undersøgelsestype
Observationel
Tilmelding (Faktiske)
11763
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
20 år til 93 år (Voksen, Ældre voksen)
Tager imod sunde frivillige
Ja
Køn, der er berettiget til at studere
Alle
Prøveudtagningsmetode
Sandsynlighedsprøve
Studiebefolkning
Of the 11,763 participants, 5,344 male and 6,419 female were enrolled, ranging from 20 to 93 years old.
People who consumed the potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes accounted for 57.3%, 15.0%, 51.8%, and 28.1%, respectively.
There were about 90.4% people who consumed the potatoes through the stir-frying method.
Beskrivelse
Inclusion Criteria:
- Adults aged 20-93 with complete data on diet and follow-up time
- Adults with no chronic disease history
Exclusion Criteria:
- Adults aged < 20 years
- Identified to be pregnant
- Previously diagnosed with hypertension, cancers, infarction, apoplexy, and diabetes
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
---|---|---|
Hypertension
Tidsramme: From entry into the study (baseline: 1989-2009) until 2011
|
Incidence of hypertension, on basis of self-reported physician diagnosis, systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, or previous diagnose of hypertension by a physician or current use of anti-hypertensive drugs
|
From entry into the study (baseline: 1989-2009) until 2011
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
---|---|---|
Potato consumption
Tidsramme: From entry into the study (baseline: 1989-2009) until 2011
|
The frequency and the quantity of daily average consumption of total potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes (g/day) based on 3-day 24-hr recall
|
From entry into the study (baseline: 1989-2009) until 2011
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Sponsor
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Faktiske)
1. januar 1989
Primær færdiggørelse (Faktiske)
31. december 2011
Studieafslutning (Faktiske)
1. februar 2018
Datoer for studieregistrering
Først indsendt
2. februar 2018
Først indsendt, der opfyldte QC-kriterier
12. februar 2018
Først opslået (Faktiske)
13. februar 2018
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
13. februar 2018
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
12. februar 2018
Sidst verificeret
1. februar 2018
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- Potato-CHNS-Cohort
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